2. Gene
  3. DAGLA - diacylglycerol lipase alpha Gene

DAGLA - diacylglycerol lipase alpha Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NSDDR; C11orf11; DAGLALPHA; DAGL(ALPHA)

Gene ID: 747 | Gene type: protein coding

About DAGLA

Cytogenetic location: 11q12.2 Genomic coordinates (GRCh38): 11:61,680,391-61,747,001 (from NCBI)

This gene has 2 transcripts (splice variants), 195 orthologues and 3 paralogues. Broad expression in brain (RPKM 6.7), colon (RPKM 2.0) and 20 other tissues.

Summary

This gene encodes a diacylglycerol Lipase. The encoded Enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.[provided by RefSeq, Nov 2010]

DAGLA Products(1)

mRNA Protein Name
NM_006133.3 NP_006124.1 diacylglycerol lipase-alpha

DAGLA Protein Structure

Lipase_3

Lipase_3: Lipase (class 3) (394 - 529)

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  • 1042 a.a.
Protein Preferred Names Protein Names

diacylglycerol lipase-alpha

DAGL-alpha

Related Diseases

Diseases Alias
Spinocerebellar Ataxia 20

Spinocerebellar Ataxia Type 20

SCA20

Spinocerebellar Ataxia With Dysphonia

Spinocerebellar Ataxia With Spasmodic Cough

Chromosome 11q12 Duplication Syndrome, 260-Kb

Chromosome 11q12 Duplication Syndrome 260-Kb
Spasmodic Dysphonia

Adductor Spasmodic Dysphonia

Laryngeal Dystonia

Spastic Dysphonia

Abductor Spasmodic Dysphonia

Laryngeal Dyskinesia

Mixed Spasmodic Dysphonia

Abductor Spastic Dysphonia

Adductor Spastic Dysphonia
Cannabis Abuse

Marijuana Abuse
Cannabis Dependence

Marijuana Abuse

Cannabinoid Addiction

Cannabinoid Dependence

Cannabis Addiction
Hallucinogen Dependence

Hallucinogen Addiction
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03520 DAGLA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DAGLA MGD MGI:2677061
Bos taurus DAGLA VGNC VGNC:27872
Canis familiaris DAGLA VGNC VGNC:39764
Rattus norvegicus DAGLA RGD RGD:1359461
Felis catus DAGLA VGNC VGNC:61332
Macaca mulatta DAGLA VGNC VGNC:107444