2. Gene
  3. SLMAP - sarcolemma associated protein Gene

SLMAP - sarcolemma associated protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SLAP

Gene ID: 7871 | Gene type: protein coding

About SLMAP

Cytogenetic location: 3p14.3 Genomic coordinates (GRCh38): 3:57,756,309-57,930,013 (from NCBI)

This gene has 40 transcripts (splice variants), 209 orthologues, 2 paralogues and is associated with 1 phenotype. Ubiquitous expression in heart (RPKM 29.5), esophagus (RPKM 29.0) and 24 other tissues.

Summary

This gene encodes a component of a conserved striatin-interacting Phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and Apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

SLMAP Products(28)

mRNA Protein Name
NM_001304420.3 NP_001291349.1 sarcolemmal membrane-associated protein isoform a
NM_001304421.2 NP_001291350.1 sarcolemmal membrane-associated protein isoform c
NM_001304422.3 NP_001291351.1 sarcolemmal membrane-associated protein isoform d
NM_001304423.3 NP_001291352.1 sarcolemmal membrane-associated protein isoform e
NM_001311178.2 NP_001298107.1 sarcolemmal membrane-associated protein isoform f
NM_001311179.2 NP_001298108.1 sarcolemmal membrane-associated protein isoform g
NM_001377538.1 NP_001364467.1 sarcolemmal membrane-associated protein isoform h
NM_001377539.1 NP_001364468.1 sarcolemmal membrane-associated protein isoform i
NM_001377540.1 NP_001364469.1 sarcolemmal membrane-associated protein isoform j
NM_001377541.1 NP_001364470.1 sarcolemmal membrane-associated protein isoform k
NM_001377542.1 NP_001364471.1 sarcolemmal membrane-associated protein isoform q
NM_001377545.1 NP_001364474.1 sarcolemmal membrane-associated protein isoform l
NM_001377549.1 NP_001364478.1 sarcolemmal membrane-associated protein isoform n
NM_001377551.1 NP_001364480.1 sarcolemmal membrane-associated protein isoform aa
NM_001377552.1 NP_001364481.1 sarcolemmal membrane-associated protein isoform o
NM_001377555.1 NP_001364484.1 sarcolemmal membrane-associated protein isoform p
NM_001377557.1 NP_001364486.1 sarcolemmal membrane-associated protein isoform c
NM_001377559.1 NP_001364488.1 sarcolemmal membrane-associated protein isoform r
NM_001377562.1 NP_001364491.1 sarcolemmal membrane-associated protein isoform bb
NM_001377921.1 NP_001364850.1 sarcolemmal membrane-associated protein isoform s
NM_001377922.1 NP_001364851.1 sarcolemmal membrane-associated protein isoform t
NM_001377923.1 NP_001364852.1 sarcolemmal membrane-associated protein isoform u
NM_001377924.1 NP_001364853.1 sarcolemmal membrane-associated protein isoform v
NM_001377925.1 NP_001364854.1 sarcolemmal membrane-associated protein isoform w
NM_001377926.1 NP_001364855.1 sarcolemmal membrane-associated protein isoform x
NM_001377927.1 NP_001364856.1 sarcolemmal membrane-associated protein isoform y
NM_001377928.1 NP_001364857.1 sarcolemmal membrane-associated protein isoform z
NM_007159.5 NP_009090.2 sarcolemmal membrane-associated protein isoform b

SLMAP Protein Structure

FHA

FHA: FHA domain (28 - 106)

  • 0
  • 200
  • 400
  • 600
  • 828 a.a.
Protein Preferred Names Protein Names

sarcolemmal membrane-associated protein

Related Diseases

Diseases Alias
Brugada Syndrome

Sudden Unexpected Nocturnal Death Syndrome

Sudden Unexplained Nocturnal Death Syndrome

Bangungut

Brugada Type Idiopathic Ventricular Fibrillation

Pokkuri Death Syndrome

Sunds

Idiopathic Ventricular Fibrillation, Brugada Type

Sudden Unexplained Death

Dream Disease

Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome

Sudden Unexplained Death Syndrome

Suds

Sunds - [Sudden Unexplained Nocturnal Death Syndrome]
Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma
Cerebral Cavernous Malformations 3

Cerebral Cavernous Malformation 3

CCM3

Cerebral Cavernous Malformations-3

Cavernous Angiomatous Malformations

Cavernous Hemangioma Of The Brain

Cerebral Capillary Malformations

Cerebral Cavernoma

Familial Cavernous Angioma

Cerebral Cavernous Malformations, Type 3
Cerebral Cavernous Malformations

Cerebral Cavernous Malformation

Cavernous Malformations Of Cns And Retina

Cerebral Cavernous Malformation 1

Cavernous Angiomatous Malformations

Cerebral Capillary Malformations

CCM

Hyperkeratotic Cutaneous Capillary-Venous Malformations Associated With Cerebral Capillary Malformations

Familial Cavernous Angioma

Cavernous Angioma

Familial Cerebral Cavernous Malformation

Cerebral Cavernous Malformations 1

Cavernous Angioma, Familial

Cam

Cerebral Cavernous Malformations-1

Cavernoma

Central Nervous System Cavernous Hemangioma

Cerebral Cavernous Hemangioma

Familial Cavernous Hemangioma

Familial Cavernous Malformation

Familial Cerebral Cavernous Angioma

Intracerebral Cavernous Hemangioma

CCM1

Cavernous Hemangioma Of The Brain

Cerebral Cavernoma

Cerebral Cavernous Malformations, Type 1

Hemangioma, Cavernous, Central Nervous System

Hemangioma, Cavernous

Angioma, Cavernous
Long Qt Syndrome 1

Romano-Ward Syndrome

LQT1

Ward-Romano Syndrome

Rws

Ventricular Fibrillation With Prolonged Qt Interval

Wrs

Long Qt Syndrome 1, Acquired, Susceptibility To

Long Qt Syndrome 1, Acquired

Romano-Ward Long Qt Syndrome

Long Qt Syndrome Type 1

Long Qt Syndrome-1

Acquired Susceptibility To Long Qt Syndrome 1

Qt Syndrome, Long, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13380 SLMAP Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SLMAP MGD MGI:1933549
Canis familiaris SLMAP VGNC VGNC:46513
Macaca mulatta SLMAP VGNC VGNC:77723
Felis catus SLMAP VGNC VGNC:65455
Rattus norvegicus SLMAP RGD RGD:1307674
Bos taurus SLMAP VGNC VGNC:34969