PDCL3 - phosducin like 3 Gene

Homo sapiens

Also known as VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A

Gene ID: 79031 | Gene type: protein coding

About PDCL3

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:100,562,993-100,576,739 (from NCBI)

This gene has 3 transcripts (splice variants), 222 orthologues and 4 paralogues. Ubiquitous expression in appendix (RPKM 9.1), esophagus (RPKM 8.2) and 25 other tissues.

Summary

This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

PDCL3 Products(1)

mRNA	Protein	Name
NM_024065.5	NP_076970.1	phosducin-like protein 3

PDCL3 Protein Structure

Phosducin

0
100
200
239 a.a.

Protein Preferred Names

Protein Names

phosducin-like protein 3

IAP-associated factor VIAF1

Related Diseases

Diseases

Alias

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome 1

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome	Berdon Syndrome
MMIHS	Megacystis Microcolon Intestinal Hypoperistalsis Syndrome
Megacystis, Microcolon, Hypoperistalsis Syndrome	Visceral Myopathy
Mmih Syndrome	Megacystis-Microcolon-Intestinal Hypoperistalsis-Hydronephrosis Syndrome
MMIHS1	Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome, Mmih
Mmhs

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10198	PDCL3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	PDCL3	VGNC	VGNC:44344
Rattus norvegicus	PDCL3	RGD	RGD:1309663
Mus musculus	PDCL3	MGD	MGI:1916083
Bos taurus	PDCL3	VGNC	VGNC:32667

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