SAP130 - Sin3A associated protein 130 Gene

Homo sapiens

Gene ID: 79595 | Gene type: protein coding

About SAP130

Cytogenetic location: 2q14.3 Genomic coordinates (GRCh38): 2:127,941,222-128,028,059 (from NCBI)

This gene has 6 transcripts (splice variants) and 228 orthologues. Broad expression in testis (RPKM 33.8), bone marrow (RPKM 7.4) and 24 other tissues.

Summary

SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]

SAP130 Products(7)

mRNA	Protein	Name
NM_001145928.2	NP_001139400.1	histone deacetylase complex subunit SAP130 isoform a
NM_001330299.2	NP_001317228.1	histone deacetylase complex subunit SAP130 isoform c
NM_001330300.2	NP_001317229.1	histone deacetylase complex subunit SAP130 isoform d
NM_001330301.2	NP_001317230.1	histone deacetylase complex subunit SAP130 isoform e
NM_001330302.2	NP_001317231.1	histone deacetylase complex subunit SAP130 isoform f
NM_001330303.2	NP_001317232.1	histone deacetylase complex subunit SAP130 isoform g
NM_024545.4	NP_078821.2	histone deacetylase complex subunit SAP130 isoform b

Protein Preferred Names

Protein Names

histone deacetylase complex subunit SAP130

130 kDa Sin3-associated polypeptide

Related Diseases

Diseases

Alias

Pleuropneumonia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12437	SAP130 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SAP130	VGNC	VGNC:45858
Mus musculus	SAP130	MGD	MGI:1919782
Bos taurus	SAP130	VGNC	VGNC:34280
Macaca mulatta	SAP130	VGNC	VGNC:77127
Felis catus	SAP130	VGNC	VGNC:64868
Rattus norvegicus	SAP130	RGD	RGD:1311657
Others	SAP130	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.