2. Gene
  3. FASTKD1 - FAST kinase domains 1 Gene

FASTKD1 - FAST kinase domains 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79675 | Gene type: protein coding

About FASTKD1

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:169,528,508-169,573,865 (from NCBI)

This gene has 10 transcripts (splice variants), 192 orthologues and 5 paralogues. Ubiquitous expression in heart (RPKM 4.3), duodenum (RPKM 3.9) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in mitochondrial RNA metabolic process and regulation of mitochondrial mRNA stability. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

FASTKD1 Products(5)

mRNA Protein Name
NM_001281476.3 NP_001268405.1 FAST kinase domain-containing protein 1, mitochondrial isoform 2
NM_001322046.2 NP_001308975.1 FAST kinase domain-containing protein 1, mitochondrial isoform 1
NM_001322048.2 NP_001308977.1 FAST kinase domain-containing protein 1, mitochondrial isoform 3
NM_001322049.2 NP_001308978.1 FAST kinase domain-containing protein 1, mitochondrial isoform 4
NM_024622.6 NP_078898.3 FAST kinase domain-containing protein 1, mitochondrial isoform 1

FASTKD1 Protein Structure

FAST_1

FAST_1: FAST kinase-like protein, subdomain 1 (575 - 643)

FAST_2

FAST_2: FAST kinase-like protein, subdomain 2 (657 - 743)

RAP

RAP: RAP domain (781 - 837)

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  • 847 a.a.
Protein Preferred Names Protein Names

FAST kinase domain-containing protein 1, mitochondrial

Related Diseases

Diseases Alias
Glaucoma 1, Open Angle, B

GLC1B

Glaucoma 1b, Primary Open Angle, Adult Onset
Mitochondrial Encephalomyopathy

Mitochondrial Encephalomyopathies

Encephalomyopathy, Mitochondrial
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04757 FASTKD1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FASTKD1 VGNC VGNC:28873
Rattus norvegicus FASTKD1 RGD RGD:1563531
Canis familiaris FASTKD1 VGNC VGNC:40738
Felis catus FASTKD1 VGNC VGNC:62154
Mus musculus FASTKD1 MGD MGI:2444596
Macaca mulatta FASTKD1 VGNC VGNC:72580