2. Gene
  3. FOXRED2 - FAD dependent oxidoreductase domain containing 2 Gene

FOXRED2 - FAD dependent oxidoreductase domain containing 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ERFAD

Gene ID: 80020 | Gene type: protein coding

About FOXRED2

Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:36,487,190-36,507,040 (from NCBI)

This gene has 18 transcripts (splice variants), 212 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 9.7), ovary (RPKM 6.3) and 24 other tissues.

Summary

Enables flavin adenine dinucleotide binding activity. Involved in ubiquitin-dependent ERAD pathway. Located in endoplasmic reticulum lumen. [provided by Alliance of Genome Resources, Apr 2022]

FOXRED2 Products(4)

mRNA Protein Name
NM_001102371.2 NP_001095841.1 FAD-dependent oxidoreductase domain-containing protein 2 isoform 1 precursor
NM_001363041.2 NP_001349970.1 FAD-dependent oxidoreductase domain-containing protein 2 isoform 2 precursor
NM_001363042.2 NP_001349971.1 FAD-dependent oxidoreductase domain-containing protein 2 isoform 2 precursor
NM_024955.6 NP_079231.4 FAD-dependent oxidoreductase domain-containing protein 2 isoform 1 precursor

FOXRED2 Protein Structure

Pyr_redox_3

Pyr_redox_3: Pyridine nucleotide-disulphide oxidoreductase (34 - 249)

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  • 684 a.a.
Protein Preferred Names Protein Names

FAD-dependent oxidoreductase domain-containing protein 2

ER flavoprotein associated with degradation

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05081 FOXRED2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris FOXRED2 VGNC VGNC:40972
Bos taurus FOXRED2 VGNC VGNC:29107
Rattus norvegicus FOXRED2 RGD RGD:1306763
Felis catus FOXRED2 VGNC VGNC:62349
Macaca mulatta FOXRED2 VGNC VGNC:84769
Mus musculus FOXRED2 MGD MGI:106315