2. Gene
  3. MOGAT2 - monoacylglycerol O-acyltransferase 2 Gene

MOGAT2 - monoacylglycerol O-acyltransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as hDC5; MGAT2; DGAT2L5; DGAT2L5.

Gene ID: 80168 | Gene type: protein coding

About MOGAT2

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:75,717,838-75,732,953 (from NCBI)

This gene has 4 transcripts (splice variants), 262 orthologues and 6 paralogues. Biased expression in small intestine (RPKM 52.4), duodenum (RPKM 48.1) and 2 other tissues.

Summary

The protein encoded by this gene is an Enzyme that catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. The encoded protein is important in the uptake of dietary fat by the small intestine. This protein forms a complex with diacylglycerol O-acyltransferase 2 in the endoplasmic reticulum, and this complex catalyzes the synthesis of triacylglycerol. [provided by RefSeq, Dec 2015]

MOGAT2 Products(1)

mRNA Protein Name
NM_025098.4 NP_079374.2 2-acylglycerol O-acyltransferase 2

MOGAT2 Protein Structure

DAGAT

DAGAT: Diacylglycerol acyltransferase (41 - 333)

  • 0
  • 100
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  • 300
  • 334 a.a.
Protein Preferred Names Protein Names

2-acylglycerol O-acyltransferase 2

acyl-CoA:monoacylglycerol acyltransferase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08585 MOGAT2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MOGAT2 MGD MGI:2663253
Felis catus MOGAT2 VGNC VGNC:63551
Canis familiaris MOGAT2 VGNC VGNC:43309
Macaca mulatta MOGAT2 VGNC VGNC:74806
Rattus norvegicus MOGAT2 RGD RGD:1598060