CPEB4 - cytoplasmic polyadenylation element binding protein 4 Gene

Homo sapiens

Also known as CPE-BP4; hCPEB-4

Gene ID: 80315 | Gene type: protein coding

About CPEB4

Cytogenetic location: 5q35.2 Genomic coordinates (GRCh38): 5:173,888,349-173,961,980 (from NCBI)

This gene has 13 transcripts (splice variants), 285 orthologues and 3 paralogues. Ubiquitous expression in adrenal (RPKM 26.5), bone marrow (RPKM 18.8) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of cytoplasmic translation; and response to ischemia. Located in cytoplasm and nucleus. Biomarker of liver cirrhosis; portal hypertension; and primary biliary cholangitis. [provided by Alliance of Genome Resources, Apr 2022]

CPEB4 Products(5)

mRNA	Protein	Name
NM_001308189.2	NP_001295118.1	cytoplasmic polyadenylation element-binding protein 4 isoform b
NM_001308191.2	NP_001295120.1	cytoplasmic polyadenylation element-binding protein 4 isoform c
NM_001308192.2	NP_001295121.1	cytoplasmic polyadenylation element-binding protein 4 isoform d
NM_001308193.2	NP_001295122.1	cytoplasmic polyadenylation element-binding protein 4 isoform e
NM_030627.4	NP_085130.2	cytoplasmic polyadenylation element-binding protein 4 isoform a

CPEB4 Protein Structure

RRM_1

0
200
400
600
729 a.a.

Protein Preferred Names

Protein Names

cytoplasmic polyadenylation element-binding protein 4

CPE-binding protein 4

Related Diseases

Diseases

Alias

Portal Hypertension

Hypertension, Portal	Hypertension Portal
Pht - [Portal Hypertension]	Portal Htn

Primary Biliary Cholangitis

Primary Biliary Cirrhosis	Biliary Liver Cirrhosis
Chronic Nonsuppurative Destructive Cholangitis	Familial Primary Biliary Cirrhosis
Pbc	Hanot Syndrome
Cholestatic Cirrhosis	Biliary Cirrhosis Primary
Liver Cirrhosis, Biliary	Hanot'S Cirrhosis
Biliary Cirrhosis	Pericholangiolic Biliary Cirrhosis
Tannhauser-Magendantz Syndrome	Hanot-Rossle Syndrome
Hypertrophic Cirrhosis	Todd Cirrhosis
Hanot Cirrhosis	Charcot Cirrhosis
Mahon-Tannhauser Syndrome	Toxic Cirrhosis
Hypertrophic Biliary Cirrhosis	Monolobular Cirrhosis
Unilobar Cirrhosis	Xanthomatous Biliary Cirrhosis

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03094	CPEB4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CPEB4	VGNC	VGNC:39554
Mus musculus	CPEB4	MGD	MGI:1914829
Bos taurus	CPEB4	VGNC	VGNC:27650
Felis catus	CPEB4	VGNC	VGNC:61121
Macaca mulatta	CPEB4	VGNC	VGNC:71450
Rattus norvegicus	CPEB4	RGD	RGD:1311931

Name
Email *

	Sorry, but the email address you supplied was invalid.