CEP70 - centrosomal protein 70 Gene

Homo sapiens

Also known as BITE

Gene ID: 80321 | Gene type: protein coding

About CEP70

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:138,494,344-138,594,260 (from NCBI)

This gene has 13 transcripts (splice variants) and 197 orthologues. Broad expression in testis (RPKM 11.4), duodenum (RPKM 7.8) and 22 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in cilium assembly and regulation of microtubule Cytoskeleton organization. Located in centrosome. [provided by Alliance of Genome Resources, Apr 2022]

CEP70 Products(8)

mRNA	Protein	Name
NM_001288964.2	NP_001275893.1	centrosomal protein of 70 kDa isoform 2
NM_001288965.2	NP_001275894.1	centrosomal protein of 70 kDa isoform 3
NM_001288966.2	NP_001275895.1	centrosomal protein of 70 kDa isoform 4
NM_001288967.2	NP_001275896.1	centrosomal protein of 70 kDa isoform 5
NM_001320598.2	NP_001307527.1	centrosomal protein of 70 kDa isoform 1
NM_001320599.2	NP_001307528.1	centrosomal protein of 70 kDa isoform 6
NM_001320600.1	NP_001307529.1	centrosomal protein of 70 kDa isoform 7
NM_024491.4	NP_077817.2	centrosomal protein of 70 kDa isoform 1

Protein Preferred Names

Protein Names

centrosomal protein of 70 kDa

centrosomal protein 70kDa

Related Diseases

Diseases

Alias

Refractory Plasma Cell Neoplasm

Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Refractory Hematologic Cancer

Refractory Hematologic Malignancy

Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia	ALL
Acute Lymphocytic Leukemia	Leukemia, Acute Lymphocytic, Susceptibility To, 1
Acute Lymphoblastic Leukaemia	Precursor Lymphoblastic Lymphoma/Leukemia
Precursor Lymphoid Neoplasm	Leukemia, Acute Lymphoblastic, Susceptibility To
B-Cell Acute Lymphoblastic Leukemia	Leukemia, Acute Lymphocytic 1
Acute Lymphocytic Leukaemia	Acute Lymphoblastic Leukemia/Lymphoma
All1	Childhood Acute Lymphoblastic Leukemia
Leukemia Acute Lymphoblastic 1	Leukemia Acute Lymphoblastic B-Hyperdiploid
Leukemia Acute Lymphocytic	Leukemia Acute Lymphocytic 1
Leukemia B-Cell Acute Lymphoblastic	Leukemia T-Cell Acute Lymphoblastic
Leukemia, Acute Lymphoblastic, 3	ALL3
Lymphoblastic Leukemia Acute	Leukemia, Acute, Lymphoblastic
Precursor Cell Lymphoblastic Leukemia Lymphoma	Leukemia, Lymphocytic, Acute, L1
Leukemia, Acute Lymphoblastic, Susceptibility To, 3

Leukemia, Acute Myeloid

Acute Myeloid Leukemia	Leukemia, Acute Myelogenous
Acute Myelogenous Leukemia	AML
Leukemia, Acute Myeloid, Susceptibility To	Acute Myeloblastic Leukemia
Leukemia, Acute Myeloid, Reduced Survival In, Somatic	Acute Myeloid Leukaemia
Leukemia, Myelocytic, Acute	Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome
Secondary Aml	Acute Myelocytic Leukemia
Acute Myeloid Leukemia, Somatic	Leukemia, Acute Myeloid, Somatic
Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic	Acute Myeloblastic Leukaemia
Acute Myelogenous Leukaemia	Aml - Acute Myeloid Leukemia
Acute Myeloid Leukemia With Cebpa Somatic Mutations	Aml With Cebpa Somatic Mutations
Inherited Acute Myeloid Leukemia	Familial Aml
Inherited Aml	Pure Familial Aml
Pure Familial Acute Myeloid Leukemia	Secondary Acute Myeloid Leukemia
Therapy-Related Aml And Myelodysplastic Syndrome	Acute Myeloid Leukemia, Secondary
Acute Non-Lymphoblastic Leukemia	Acute Non-Lymphocytic Leukemia
Acute Biphenotypic Leukemia	Acute Undifferentiated Leukemia
Acute Myeloblastic Leukaemia With Multilineage Dysplasia	Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission
Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02521	CEP70 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CEP70	VGNC	VGNC:60781
Canis familiaris	CEP70	VGNC	VGNC:39135
Rattus norvegicus	CEP70	RGD	RGD:1561486
Mus musculus	CEP70	MGD	MGI:1915371
Bos taurus	CEP70	VGNC	VGNC:27211
Macaca mulatta	CEP70	VGNC	VGNC:71140

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