NDFIP1 - Nedd4 family interacting protein 1 Gene

Homo sapiens

Also known as N4WBP5

Gene ID: 80762 | Gene type: protein coding

About NDFIP1

Cytogenetic location: 5q31.3 Genomic coordinates (GRCh38): 5:142,108,779-142,154,440 (from NCBI)

This gene has 4 transcripts (splice variants), 280 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 106.7), thyroid (RPKM 68.4) and 25 other tissues.

Summary

The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008]

NDFIP1 Products(1)

mRNA	Protein	Name
NM_030571.4	NP_085048.1	NEDD4 family-interacting protein 1

NDFIP1 Protein Structure

DUF2370

0
100
200
221 a.a.

Protein Preferred Names

Protein Names

NEDD4 family-interacting protein 1

Nedd4 WW domain-binding protein 5

Related Diseases

Diseases

Alias

Congenital Myasthenic Syndrome 7

Cms7	Congenital Myasthenic Syndrome 7 Presynaptic
Myasthenic Syndrome, Congenital, Type 7, Presynaptic

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09108	NDFIP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	NDFIP1	VGNC	VGNC:63750
Canis familiaris	NDFIP1	VGNC	VGNC:43673
Rattus norvegicus	NDFIP1	RGD	RGD:1310053
Bos taurus	NDFIP1	VGNC	VGNC:31934
Mus musculus	NDFIP1	MGD	MGI:1929601
Macaca mulatta	NDFIP1	VGNC	VGNC:74979

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