Hcar2 - hydroxycarboxylic acid receptor 2 Gene

Mus musculus

Also known as HM74; Pumag; Niacr1; PUMA-G; mHM74b; Gpr109a; Gpr109b

Gene ID: 80885 | Gene type: protein coding

About Hcar2

Chromosome 5: 124,001,633-124,003,562 reverse strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 164 orthologues, 13 paralogues and is associated with 5 phenotypes.

Summary

Enables G protein-coupled receptor activity; GTP binding activity; and purinergic nucleotide receptor activity. Involved in G protein-coupled receptor signaling pathway. Is integral component of membrane. Is active in membrane. Is expressed in embryo. Orthologous to several human genes including HCAR3 (hydroxycarboxylic acid receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Hcar2 Products(1)

mRNA	Protein	Name
NM_030701.3	NP_109626.1	hydroxycarboxylic acid receptor 2

Hcar2 Protein Structure

7tmA_HCAR1-3

0
100
200
300
360 a.a.

Protein Preferred Names

Protein Names

hydroxycarboxylic acid receptor 2

G protein-coupled receptor 109A	G protein-coupled receptor 109B
G-protein coupled receptor 109	G-protein coupled receptor HM74
interferon-gamma inducible gene, Puma-g	niacin receptor 1
nicotinic acid receptor	putative seven transmembrane spanning receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-156025	HCAR2 agonist 1		/	Unkown
HY-RS06038	HCAR2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06039	Hcar2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06040	Hcar2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hcar2	NCBI	NCBI:338442

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