2. Gene
  3. ACSBG2 - acyl-CoA synthetase bubblegum family member 2 Gene

ACSBG2 - acyl-CoA synthetase bubblegum family member 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BGR; BRGL; PRTDNY3; PRTD-NY3

Gene ID: 81616 | Gene type: protein coding

About ACSBG2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,135,633-6,193,091 (from NCBI)

This gene has 15 transcripts (splice variants), 263 orthologues and 12 paralogues. Restricted expression toward testis (RPKM 79.4).

Summary

Enables acyl-CoA hydrolase activity and arachidonate-CoA ligase activity. Acts upstream of or within fatty acid metabolic process. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

ACSBG2 Products(6)

mRNA Protein Name
NM_001289177.2 NP_001276106.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform a
NM_001289178.2 NP_001276107.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform a
NM_001289179.2 NP_001276108.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform b
NM_001289180.2 NP_001276109.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform c
NM_001321384.2 NP_001308313.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform d
NM_030924.5 NP_112186.3 long-chain-fatty-acid--CoA ligase ACSBG2 isoform a

ACSBG2 Protein Structure

AMP-binding

AMP-binding: AMP-binding enzyme (57 - 518)

  • 0
  • 200
  • 400
  • 600
  • 666 a.a.
Protein Preferred Names Protein Names

long-chain-fatty-acid--CoA ligase ACSBG2

arachidonate--CoA ligase ACSBG2

Related Diseases

Diseases Alias
Ceroid Lipofuscinosis, Neuronal, 1

Neuronal Ceroid Lipofuscinosis 1

CLN1

Infantile Neuronal Ceroid Lipofuscinosis

Cln1 Disease

Santavuori-Haltia Disease

Ceroid Lipofuscinosis, Neuronal, 1, Variable Age At Onset

Neuronal Ceroid Lipofuscinosis 1 Variable Age Of Onset

Ceroid Lipofuscinosis Neuronal 1

Cln1 Variable Age At Onset

Infantile Batten Disease

Neuronal Ceroid Lipofuscinosis, Infantile

Hagberg-Santavuori Disease

Incl

Juvenile Neuronal Ceroid Lipofuscinosis With Granular Osmiophilic Deposits

Neuronal Ceroid Lipofuscinosis With Variable Age At Onset

Santavuori Disease

Lipofuscinosis, Ceroid, Neuronal, Type 1

Ceroid Lipofuscinosis, Neuronal 1, Infantile
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00197 ACSBG2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ACSBG2 VGNC VGNC:54569
Mus musculus ACSBG2 MGD MGI:3587728
Macaca mulatta ACSBG2 VGNC VGNC:69525
Rattus norvegicus ACSBG2 RGD RGD:1588580
Bos taurus ACSBG2 VGNC VGNC:25561