2. Gene
  3. SFXN3 - sideroflexin 3 Gene

SFXN3 - sideroflexin 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SFX3; SLC56A3; BA108L7.2

Gene ID: 81855 | Gene type: protein coding

About SFXN3

Cytogenetic location: 10q24.31 Genomic coordinates (GRCh38): 10:101,031,234-101,041,241 (from NCBI)

This gene has 8 transcripts (splice variants), 222 orthologues and 4 paralogues. Ubiquitous expression in small intestine (RPKM 25.7), duodenum (RPKM 19.3) and 23 other tissues.

Summary

Enables serine transmembrane transporter activity. Involved in serine import into mitochondrion. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

SFXN3 Products(10)

mRNA Protein Name
NM_001388027.1 NP_001374956.1 sideroflexin-3 isoform 2
NM_001388028.1 NP_001374957.1 sideroflexin-3 isoform 2
NM_001388029.1 NP_001374958.1 sideroflexin-3 isoform 6
NM_001388030.1 NP_001374959.1 sideroflexin-3 isoform 6
NM_001388031.1 NP_001374960.1 sideroflexin-3 isoform 6
NM_001388032.1 NP_001374961.1 sideroflexin-3 isoform 3
NM_001388033.1 NP_001374962.1 sideroflexin-3 isoform 4
NM_001388034.1 NP_001374963.1 sideroflexin-3 isoform 5
NM_001388035.1 NP_001374964.1 sideroflexin-3 isoform 5
NM_030971.6 NP_112233.3 sideroflexin-3 isoform 1

SFXN3 Protein Structure

Mtc

Mtc: Tricarboxylate carrier (19 - 325)

  • 0
  • 100
  • 200
  • 300
  • 325 a.a.
Protein Preferred Names Protein Names

sideroflexin-3

Related Diseases

Diseases Alias
Sengers Syndrome

Mitochondrial Dna Depletion Syndrome 10

Cardiomyopathy And Cataract

Cataract And Cardiomyopathy

MTDPS10

Congenital Cataract-Hypertrophic Cardiomyopathy-Mitochondrial Myopathy Syndrome

Cardiomyopathic Mitochondrial Dna Depletion Syndrome 10

Senger Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12787 SFXN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SFXN3 MGD MGI:2137679
Canis familiaris SFXN3 VGNC VGNC:46089
Felis catus SFXN3 VGNC VGNC:65071
Rattus norvegicus SFXN3 RGD RGD:620716
Bos taurus SFXN3 VGNC VGNC:34532
Macaca mulatta SFXN3 VGNC VGNC:77245