FCRL5 - Fc receptor like 5 Gene

Homo sapiens

Also known as CD307; FCRH5; IRTA2; BXMAS1; CD307e; PRO820

Gene ID: 83416 | Gene type: protein coding

About FCRL5

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:157,513,377-157,552,515 (from NCBI)

This gene has 8 transcripts (splice variants), 83 orthologues and 17 paralogues. Biased expression in lymph node (RPKM 14.3), spleen (RPKM 11.3) and 8 other tissues.

Summary

This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

FCRL5 Products(2)

mRNA	Protein	Name
NM_001195388.2	NP_001182317.1	Fc receptor-like protein 5 isoform 2 precursor
NM_031281.3	NP_112571.2	Fc receptor-like protein 5 isoform 1 precursor

FCRL5 Protein Structure

Ig_2

Ig_3

Ig_2

0
200
400
600
800
977 a.a.

Protein Preferred Names

Protein Names

Fc receptor-like protein 5

fc receptor homolog 5

Recombinant FCRL5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77651	FcRH5/FcRL5 Protein, Human (HEK293, His-Avi)	Q96RD9-1 (Q16-G851)	≥95%
HY-P700302	FcRH5/FcRL5 Protein, Human (HEK293, His)	AAK93971 (Q16-G851)	> 95% as determined by Tris-Bis PAGE.

Related Diseases

Diseases

Alias

Hairy Cell Leukemia

Hcl-V	Hairy Cell Leukemia Variant
Hairy Cell Leukaemia Variant	Hcl
Leukemic Reticuloendotheliosis	Leukemic Reticuloendotheliosis Variant
Prolymphocytic Variant Of Hcl	Prolymphocytic Variant Of Hairy Cell Leukemia
Leukemia Hairy Cell	Leukemia, Hairy Cell
Leukaemic Reticuloendotheliosis	Lre - [Leukemic Reticuloendotheliosis]
Hairy-Cell Leukaemia, Nos	Hcl - [Hairy Cell Leukaemia]
Hairy-Cell Leukaemia Without Mention Of Remission

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Burkitt Lymphoma

Burkitt'S Lymphoma	BL
Burkitt Lymphoma, Somatic	Burkitt Lymphoma/Leukaemia
Burkitt'S Tumor	Burkitt'S Tumor Or Lymphoma
Malignant Lymphoma, Burkitt'S Type	Small Non-Cleaved Cell Lymphoma, Burkitt'S Type
Small Non-Cleaved Cell Lymphoma	Burkitt Tumor
Burkitts Lymphoma	Lymphoma, Small Noncleaved-Cell
Burkitt Tumour	Diffuse Small Noncleaved Malignant Burkitt Lymphoma
Malignant Burkitt Lymphoma	“Burkitt-Like” Lymphoma
Undifferentiated Burkitt Lymphoma	Small Noncleaved Cell Burkitt Lymphoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04846	FCRL5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	FCRL5	RGD	RGD:1589379
Bos taurus	FCRL5	VGNC	VGNC:59181
Canis familiaris	FCRL5	VGNC	VGNC:49722
Felis catus	FCRL5	VGNC	VGNC:62216
Macaca mulatta	FCRL5	VGNC	VGNC:99950
Mus musculus	FCRL5	MGD	MGI:3053558
Others	FCRL5	NCBI

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