2. Gene
  3. SLC25A31 - solute carrier family 25 member 31 Gene

SLC25A31 - solute carrier family 25 member 31 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as AAC4; ANT4; ANT 4; SFEC35kDa

Gene ID: 83447 | Gene type: protein coding

About SLC25A31

Cytogenetic location: 4q28.1 Genomic coordinates (GRCh38): 4:127,730,400-127,774,292 (from NCBI)

This gene has 1 transcript (splice variant), 118 orthologues and 49 paralogues. Restricted expression toward testis (RPKM 32.1).

Summary

The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar Cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

SLC25A31 Products(2)

mRNA Protein Name
NM_001318467.2 NP_001305396.1 ADP/ATP translocase 4 isoform 2
NM_031291.4 NP_112581.1 ADP/ATP translocase 4 isoform 1

SLC25A31 Protein Structure

Mito_carr

Mito_carr: Mitochondrial carrier protein (18 - 112)

Mito_carr

Mito_carr: Mitochondrial carrier protein (123 - 216)

Mito_carr

Mito_carr: Mitochondrial carrier protein (219 - 309)

  • 0
  • 100
  • 200
  • 315 a.a.
Protein Preferred Names Protein Names

ADP/ATP translocase 4

ADP,ATP carrier protein 4

Related Diseases

Diseases Alias
Acute Laryngitis

Acute Laryngitis Nos

Laryngeal Inflammation

Laryngitis Nos

Larynx Inflammation
Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13113 SLC25A31 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC25A31 VGNC VGNC:34757
Canis familiaris SLC25A31 VGNC VGNC:46305
Mus musculus SLC25A31 MGD MGI:1920583
Felis catus SLC25A31 VGNC VGNC:65269
Rattus norvegicus SLC25A31 RGD RGD:1596195
Macaca mulatta SLC25A31 VGNC VGNC:107199