2. Gene
  3. KATNAL2 - katanin catalytic subunit A1 like 2 Gene

KATNAL2 - katanin catalytic subunit A1 like 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 83473 | Gene type: protein coding

About KATNAL2

Cytogenetic location: 18q21.1 Genomic coordinates (GRCh38): 18:46,917,594-47,102,243 (from NCBI)

This gene has 25 transcripts (splice variants), 202 orthologues and 9 paralogues. Broad expression in testis (RPKM 2.3), thyroid (RPKM 1.9) and 23 other tissues.

Summary

Predicted to enable microtubule-severing ATPase activity. Predicted to be involved in cytoplasmic microtubule organization. Located in cytoplasm; microtubule; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]

KATNAL2 Products(14)

mRNA Protein Name
NM_001353899.1 NP_001340828.1 katanin p60 ATPase-containing subunit A-like 2 isoform 1
NM_001353900.1 NP_001340829.1 katanin p60 ATPase-containing subunit A-like 2 isoform 2
NM_001353901.1 NP_001340830.1 katanin p60 ATPase-containing subunit A-like 2 isoform 3
NM_001353902.1 NP_001340831.1 katanin p60 ATPase-containing subunit A-like 2 isoform 4
NM_001353903.1 NP_001340832.1 katanin p60 ATPase-containing subunit A-like 2 isoform 6
NM_001353904.1 NP_001340833.1 katanin p60 ATPase-containing subunit A-like 2 isoform 7
NM_001353905.1 NP_001340834.1 katanin p60 ATPase-containing subunit A-like 2 isoform 8
NM_001353906.1 NP_001340835.1 katanin p60 ATPase-containing subunit A-like 2 isoform 8
NM_001353907.1 NP_001340836.1 katanin p60 ATPase-containing subunit A-like 2 isoform 9
NM_001353908.1 NP_001340837.1 katanin p60 ATPase-containing subunit A-like 2 isoform 10
NM_001353909.1 NP_001340838.1 katanin p60 ATPase-containing subunit A-like 2 isoform 11
NM_001367621.1 NP_001354550.1 katanin p60 ATPase-containing subunit A-like 2 isoform 13
NM_001387690.1 NP_001374619.1 katanin p60 ATPase-containing subunit A-like 2 isoform 13
NM_031303.3 NP_112593.2 katanin p60 ATPase-containing subunit A-like 2 isoform 5

KATNAL2 Protein Structure

LisH

LisH: LisH (27 - 53)

AAA

AAA: ATPase family associated with various cellular activities (AAA) (290 - 421)

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  • 538 a.a.
Protein Preferred Names Protein Names

katanin p60 ATPase-containing subunit A-like 2

katanin catalytic subunit A like 2

Related Diseases

Diseases Alias
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
Fraser Syndrome 2

FRASRS2
Ceroid Lipofuscinosis, Neuronal, 8

Neuronal Ceroid Lipofuscinosis 8

CLN8

Cln8 Disease

Epilepsy Mental Deterioration Finnish Type

Northern Epilepsy

Cln8 Disease, Epmr

Cln8 Disease, Northern Epilepsy Variant

Cln8 Disease, Late Infantile

Ceroid Lipofuscinosis Neuronal 8

Ncl, Northern Epilepsy Variant

Neuronal Ceroid Lipofuscinosis, Northern Epilepsy Variant

Progressive Epilepsy - Intellectual Disability, Finnish Type

Progressive Epilepsy-Intellectual Disability Syndrome, Finnish Type

Turkish Variant Late Infantile Ncl

Ceroid Lipofuscinosis, Neuronal 8

Lipofuscinosis, Ceroid, Neuronal, Type 8

Northern Epilepsy Syndrome
Bainbridge-Ropers Syndrome

BRPS

Severe Feeding Difficulties-Failure To Thrive-Microcephaly Due To Asxl3 Deficiency Syndrome

Asxl3-Related Disorder
Meningioma, Familial

Meningioma

Familial Meningioma

Meningioma, Familial, Susceptibility To

Meningeal Neoplasm

Meningeal Neoplasms

Meningiomas

Meningioma, Nf2-Related, Somatic

Meningioma, Sis-Related

Meningothelial Cell Tumor

Neoplasm Of The Meninges

Primary Meningeal Tumor

Familial Multiple Meningioma

MNGMA

Meningioma, Benign, No Icd-O Subtype

Intracranial Meningioma

Meningothelial Cell Neoplasm

Supratentorial Meningioma

Primary Neoplasm Of Spinal Meninges

Benign Intracranial Meningioma

Benign Meningioma

Meningeal Tumours

Meningeal Sarcoma Of Unspecified Site

Meningothelial Sarcoma Of Unspecified Site
Coffin-Siris Syndrome 1

Coffin-Siris Syndrome

Fifth Digit Syndrome

Css

CSS1

Mrd12

Mental Retardation, Autosomal Dominant 12

Hhid

Dwarfism-Onychodysplasia

Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features

Autosomal Dominant Mental Retardation 12

Short Stature-Onychodysplasia.

Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx

Mental Retardation With Hypoplastic Fifth Fingernails And Toenails

Short Stature-Onychodysplasia

Coffin-Siris Syndrome, Type 1

Mental Retardation, Autosomal Dominant, Type 12
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07086 KATNAL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta KATNAL2 VGNC VGNC:73904
Bos taurus KATNAL2 VGNC VGNC:30407
Mus musculus KATNAL2 MGD MGI:1924234
Rattus norvegicus KATNAL2 RGD RGD:1564708
Felis catus KATNAL2 VGNC VGNC:63029
Canis familiaris KATNAL2 VGNC VGNC:42218