2. Gene
  3. KBTBD7 - kelch repeat and BTB domain containing 7 Gene

KBTBD7 - kelch repeat and BTB domain containing 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 84078 | Gene type: protein coding

About KBTBD7

Cytogenetic location: 13q14.11 Genomic coordinates (GRCh38): 13:41,189,834-41,194,569 (from NCBI)

This gene has 1 transcript (splice variant), 81 orthologues and 54 paralogues.

Summary

The protein encoded by this gene is a transcriptional activator, having been shown to increase the transcription of activator protein-1 and serum response element. The encoded protein can also form a complex with KBTBD6 and CUL3, which regulates the ubiquitylation and degradation of TIAM1, which is a regulator of RAC1. [provided by RefSeq, Jul 2016]

KBTBD7 Products(1)

mRNA Protein Name
NM_032138.7 NP_115514.2 kelch repeat and BTB domain-containing protein 7

KBTBD7 Protein Structure

BTB

BTB: BTB/POZ domain (54 - 166)

BACK

BACK: BTB And C-terminal Kelch (173 - 273)

Kelch_1

Kelch_1: Kelch motif (427 - 469)

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  • 684 a.a.
Protein Preferred Names Protein Names

kelch repeat and BTB domain-containing protein 7

kelch repeat and BTB (POZ) domain containing 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07095 KBTBD7 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KBTBD7 VGNC VGNC:56746
Felis catus KBTBD7 VGNC VGNC:102238
Macaca mulatta KBTBD7 VGNC VGNC:73903
Bos taurus KBTBD7 VGNC VGNC:53820
Mus musculus KBTBD7 MGD MGI:2685141
Rattus norvegicus KBTBD7 RGD RGD:6501695
Others KBTBD7 NCBI