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  3. FBXO30 - F-box protein 30 Gene

FBXO30 - F-box protein 30 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Fbx30

Gene ID: 84085 | Gene type: protein coding

About FBXO30

Cytogenetic location: 6q24.3 Genomic coordinates (GRCh38): 6:145,793,502-145,814,795 (from NCBI)

This gene has 1 transcript (splice variant), 204 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 3.5), testis (RPKM 3.3) and 25 other tissues.

Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008]

FBXO30 Products(2)

mRNA Protein Name
NM_001348092.2 NP_001335021.1 F-box only protein 30
NM_032145.5 NP_115521.3 F-box only protein 30

FBXO30 Protein Structure

F-box

F-box: F-box domain (612 - 648)

  • 0
  • 200
  • 400
  • 600
  • 745 a.a.
Protein Preferred Names Protein Names

F-box only protein 30

F-box domain protein

Related Diseases

Diseases Alias
Nasopharyngeal Carcinoma

Malignant Neoplasm Of Nasopharynx

Npc

Nasopharyngeal Cancer

Nasopharyngeal Carcinoma 1

Nasopharynx Carcinoma

Nasopharyngeal Neoplasms

Npca

Carcinoma Of Nasopharynx

Malignant Nasopharyngeal Tumor

Nasopharynx Cancer

Squamous Cell Carcinoma Of The Nasopharynx

Nasopharyngeal Neoplasm

Cancer Of Nasopharynx
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04802 FBXO30 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta FBXO30 VGNC VGNC:72510
Rattus norvegicus FBXO30 RGD RGD:1359367
Canis familiaris FBXO30 VGNC VGNC:40772
Felis catus FBXO30 VGNC VGNC:62185
Mus musculus FBXO30 MGD MGI:1919115
Bos taurus FBXO30 VGNC VGNC:28903