EVA1A - eva-1 homolog A, regulator of programmed cell death Gene

Homo sapiens

Also known as FAM176A; TMEM166

Gene ID: 84141 | Gene type: protein coding

About EVA1A

Cytogenetic location: 2p12 Genomic coordinates (GRCh38): 2:75,492,318-75,569,719 (from NCBI)

This gene has 11 transcripts (splice variants), 263 orthologues and 1 paralogue. Biased expression in liver (RPKM 20.6), lung (RPKM 8.7) and 7 other tissues.

Summary

Predicted to be involved in apoptotic process and Autophagy. Located in intracellular membrane-bounded organelle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVA1A Products(4)

mRNA	Protein	Name
NM_001135032.2	NP_001128504.1	protein eva-1 homolog A
NM_001369524.1	NP_001356453.1	protein eva-1 homolog A
NM_001369525.1	NP_001356454.1	protein eva-1 homolog A
NM_032181.3	NP_115557.1	protein eva-1 homolog A

EVA1A Protein Structure

FAM176

0
100
152 a.a.

Protein Preferred Names

Protein Names

protein eva-1 homolog A

family with sequence similarity 176, member A

Related Diseases

Diseases

Alias

Fuchs' Endothelial Dystrophy

Fuchs Endothelial Corneal Dystrophy	Fuchs Endothelial Dystrophy
Fuchs Dystrophy	Fced
Fuchs' Corneal Dystrophy	Fuchs' Endothelial Corneal Dystrophy
Fuchs Atrophy	Fuchs Corneal Dystrophy
Endoepithelial Corneal Dystrophy	Fecd
Late Hereditary Endothelial Dystrophy	Corneal Dystrophy, Fuchs Endothelial
Dystrophy, Corneal, Fuchs Endothelial	Corneal Dystrophy, Fuchs' Endothelial, 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04571	EVA1A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	EVA1A	VGNC	VGNC:106159
Mus musculus	EVA1A	MGD	MGI:2385247
Canis familiaris	EVA1A	VGNC	VGNC:54943
Rattus norvegicus	EVA1A	RGD	RGD:1559797

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