ING5 - inhibitor of growth family member 5 Gene

Homo sapiens

Also known as p28ING5

Gene ID: 84289 | Gene type: protein coding

About ING5

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:241,687,020-241,729,478 (from NCBI)

This gene has 13 transcripts (splice variants), 216 orthologues and 4 paralogues. Ubiquitous expression in ovary (RPKM 3.6), skin (RPKM 3.2) and 25 other tissues.

Summary

This gene encodes a tumor suppressor protein that inhibits cell growth and induces Apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. [provided by RefSeq, Aug 2016]

ING5 Products(3)

mRNA	Protein	Name
NM_001330161.2	NP_001317090.1	inhibitor of growth protein 5 isoform 2
NM_001330162.2	NP_001317091.1	inhibitor of growth protein 5 isoform 3
NM_032329.6	NP_115705.2	inhibitor of growth protein 5 isoform 1

ING5 Protein Structure

ING

PHD

0
100
200
240 a.a.

Protein Preferred Names

Protein Names

inhibitor of growth protein 5

Recombinant ING5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75887	ING5 Protein, Human (His)	Q8WYH8-2 (E36-Q84)	≥95%

Related Diseases

Diseases

Alias

Ohdo Syndrome, Sbbys Variant

Say-Barber-Biesecker-Young-Simpson Syndrome	SBBYSS
Young-Simpson Syndrome	Blepharophimosis-Intellectual Disability Syndrome, Sbbys Type
Yss	Sbbys Variant Of Ohdo Syndrome
Blepharophimosis - Intellectual Disability Syndrome, Sbbys Type	Young Simpson Syndrome
Sbbyss Syndrome	Ohdo Syndrome, Say-Barber-Biesecker-Young-Simpson Variant
Blepharophimosis And Mental Retardation Syndrome, Say-Barber/Biesecker/Young-Simpson Type	Blepharophimosis-Intellectual Deficit Syndrome, Say-Barber/Biesecker/Young-Simpson Type
Bmrs Sbbys	Ohdo Syndrome, Say-Barber-Biesecker Variant
Say-Barber-Biesecker-Young-Simpson Variant Of Ohdo Syndrome	Hypothyroidism-Dysmorphism-Postaxial Polydactyly-Intellectual Disability Syndrome
Say-Barber-Biesecker Variant Of Ohdo Syndrome

Ohdo Syndrome

Young Simpson Syndrome	Ohdo Blepharophimosis Syndrome
Blepharophimosis Syndrome Ohdo Type	Blepharophimosis Intellectual Disability Syndromes
Bmrs	Blepharophimosis-Intellectual Disability Syndrome
Mental Retardation, Congenital Heart Disease, Blepharophimosis, Blepharoptosis, And Hypoplastic Teeth	Sbbys Syndrome
Say Barber Biesecker Young-Simpson Syndrome	Blepharophimosis-Intellectual Disability Syndrome, Ohdo Type
Bmrs, Ohdo Type	Blepharophimosis Syndrome, Ohdo Type
Ohdo-Madokoro-Sonoda Syndrome	Blepharophimosis - Intellectual Disability Syndrome, Ohdo Type
Blepharophimosis - Intellectual Disability Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06811	ING5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ING5	RGD	RGD:1307908
Canis familiaris	ING5	VGNC	VGNC:42019
Felis catus	ING5	VGNC	VGNC:107565
Bos taurus	ING5	VGNC	VGNC:30198
Macaca mulatta	ING5	VGNC	VGNC:73627
Mus musculus	ING5	MGD	MGI:1922816
Others	ING5	NCBI