2. Gene
  3. GINS4 - GINS complex subunit 4 Gene

GINS4 - GINS complex subunit 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SLD5

Gene ID: 84296 | Gene type: protein coding

About GINS4

Cytogenetic location: 8p11.21 Genomic coordinates (GRCh38): 8:41,529,261-41,545,030 (from NCBI)

This gene has 9 transcripts (splice variants) and 202 orthologues. Broad expression in lymph node (RPKM 2.4), appendix (RPKM 2.0) and 23 other tissues.

Summary

The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]

GINS4 Products(1)

mRNA Protein Name
NM_032336.3 NP_115712.1 DNA replication complex GINS protein SLD5

GINS4 Protein Structure

Sld5

Sld5: GINS complex protein (61 - 126)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

DNA replication complex GINS protein SLD5

SLD5 homolog

Related Diseases

Diseases Alias
Adrenal Cortical Adenocarcinoma

Adrenal Cortex Adenocarcinoma

Adrenocortical Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05433 GINS4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GINS4 VGNC VGNC:41223
Mus musculus GINS4 MGD MGI:1923847
Rattus norvegicus GINS4 RGD RGD:1307397
Bos taurus GINS4 VGNC VGNC:29363
Felis catus GINS4 VGNC VGNC:62556
Macaca mulatta GINS4 VGNC VGNC:73021