2. Gene
  3. ZGPAT - zinc finger CCCH-type and G-patch domain containing Gene

ZGPAT - zinc finger CCCH-type and G-patch domain containing Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847

Gene ID: 84619 | Gene type: protein coding

About ZGPAT

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:63,707,442-63,736,142 (from NCBI)

This gene has 11 transcripts (splice variants), 199 orthologues and 2 paralogues. Ubiquitous expression in liver (RPKM 22.1), kidney (RPKM 17.5) and 25 other tissues.

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ZGPAT Products(5)

mRNA Protein Name
NM_001083113.2 NP_001076582.1 zinc finger CCCH-type with G patch domain-containing protein isoform c
NM_001195653.2 NP_001182582.1 zinc finger CCCH-type with G patch domain-containing protein isoform c
NM_001195654.2 NP_001182583.1 zinc finger CCCH-type with G patch domain-containing protein isoform d
NM_032527.5 NP_115916.3 zinc finger CCCH-type with G patch domain-containing protein isoform a
NM_181485.3 NP_852150.2 zinc finger CCCH-type with G patch domain-containing protein isoform c

ZGPAT Protein Structure

G-patch

G-patch: G-patch domain (333 - 374)

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  • 500
  • 531 a.a.
Protein Preferred Names Protein Names

zinc finger CCCH-type with G patch domain-containing protein

g patch domain-containing protein 6

Related Diseases

Diseases Alias
Melnick-Needles Syndrome

MNS

Melnick-Needles Osteodysplasty

Osteodysplasty Of Melnick And Needles

Osteochondrodysplasias
Otopalatodigital Syndrome Spectrum Disorder

Opd Spectrum Disorder

Opsd

Fronto-Otopalatodigital Osteodysplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16066 ZGPAT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZGPAT MGD MGI:2449939
Macaca mulatta ZGPAT VGNC VGNC:98469
Canis familiaris ZGPAT VGNC VGNC:54747
Bos taurus ZGPAT VGNC VGNC:57036
Rattus norvegicus ZGPAT RGD RGD:1310801