SPZ1 - spermatogenic leucine zipper 1 Gene

Homo sapiens

Also known as CILD38; NYD-TSP1; PPP1R148

Gene ID: 84654 | Gene type: protein coding

About SPZ1

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:80,320,002-80,321,842 (from NCBI)

This gene has 2 transcripts (splice variants), 119 orthologues and 10 paralogues.

Summary

This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011]

SPZ1 Products(1)

mRNA	Protein	Name
NM_032567.4	NP_115956.3	spermatogenic leucine zipper protein 1

Protein Preferred Names

Protein Names

spermatogenic leucine zipper protein 1

protein phosphatase 1, regulatory subunit 148

Related Diseases

Diseases

Alias

Ciliary Dyskinesia, Primary, 13

Primary Ciliary Dyskinesia 13	CILD13
Primary Ciliary Dyskinesia 13 With Or Without Situs Inversus	Ciliary Dyskinesia, Primary, 13, With Or Without Situs Inversus
Ics13	Immotile Cilia Syndrome 13
Dyskinesia, Ciliary, Primary, 13

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13742	SPZ1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SPZ1	MGD	MGI:1930801
Canis familiaris	SPZ1	VGNC	VGNC:46785
Felis catus	SPZ1	VGNC	VGNC:102333
Bos taurus	SPZ1	VGNC	VGNC:35263
Rattus norvegicus	SPZ1	RGD	RGD:1562395

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