2. Gene
  3. DPY30 - dpy-30 histone methyltransferase complex regulatory subunit Gene

DPY30 - dpy-30 histone methyltransferase complex regulatory subunit Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Cps25; Saf19; HDPY-30

Gene ID: 84661 | Gene type: protein coding

About DPY30

Cytogenetic location: 2p22.3 Genomic coordinates (GRCh38): 2:32,011,649-32,039,835 (from NCBI)

This gene has 7 transcripts (splice variants) and 216 orthologues. Ubiquitous expression in thyroid (RPKM 7.5), adrenal (RPKM 7.3) and 25 other tissues.

Summary

This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016]

DPY30 Products(3)

mRNA Protein Name
NM_001321209.2 NP_001308138.1 protein dpy-30 homolog isoform 1
NM_001321210.2 NP_001308139.1 protein dpy-30 homolog isoform 2
NM_032574.4 NP_115963.1 protein dpy-30 homolog isoform 1

DPY30 Protein Structure

Dpy-30

Dpy-30: Dpy-30 motif (52 - 92)

  • 0
  • 99 a.a.
Protein Preferred Names Protein Names

protein dpy-30 homolog

dpy-30 homolog

Related Diseases

Diseases Alias
Kabuki Syndrome 1

Kabuki Syndrome

Niikawa-Kuroki Syndrome

Kabuki Make-Up Syndrome

Kms

KABUK1

Kabuki Make Up Syndrome

Nks

Kabuki Makeup Syndrome

Kabuki Syndrome, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03978 DPY30 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus DPY30 VGNC VGNC:80086
Bos taurus DPY30 VGNC VGNC:50608
Mus musculus DPY30 MGD MGI:1913560
Rattus norvegicus DPY30 RGD RGD:708575
Canis familiaris DPY30 VGNC VGNC:49106
Macaca mulatta DPY30 VGNC VGNC:71898
Others DPY30 NCBI