NFKBID - NFKB inhibitor delta Gene

Homo sapiens

Also known as IkBNS; TA-NFKBH; IkappaBNS

Gene ID: 84807 | Gene type: protein coding

About NFKBID

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,887,952-35,902,303 (from NCBI)

This gene has 11 transcripts (splice variants), 195 orthologues and 3 paralogues. Broad expression in bone marrow (RPKM 9.7), appendix (RPKM 2.8) and 19 other tissues.

Summary

Predicted to enable NF-kappaB binding activity. Predicted to be involved in T cell receptor signaling pathway; positive regulation of T-helper 17 cell differentiation; and regulation of gene expression. Predicted to act upstream of or within several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of T cell differentiation in thymus; and positive regulation of thymocyte apoptotic process. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NFKBID Products(5)

mRNA	Protein	Name
NM_001321831.2	NP_001308760.1	NF-kappa-B inhibitor delta isoform 2
NM_001365705.1	NP_001352634.1	NF-kappa-B inhibitor delta isoform 1
NM_001365706.2	NP_001352635.1	NF-kappa-B inhibitor delta isoform 4
NM_032721.3	NP_116110.2	NF-kappa-B inhibitor delta isoform 3
NM_139239.3	NP_640332.1	NF-kappa-B inhibitor delta isoform 1

NFKBID Protein Structure

Ank_2

0
100
200
313 a.a.

Protein Preferred Names

Protein Names

NF-kappa-B inhibitor delta

I-kappa-B-delta

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09262	NFKBID Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	NFKBID	VGNC	VGNC:53742
Felis catus	NFKBID	VGNC	VGNC:63790
Macaca mulatta	NFKBID	VGNC	VGNC:75179
Bos taurus	NFKBID	VGNC	VGNC:32047
Mus musculus	NFKBID	MGD	MGI:3041243
Rattus norvegicus	NFKBID	RGD	RGD:1308055

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