2. Gene
  3. LRCH3 - leucine rich repeats and calponin homology domain containing 3 Gene

LRCH3 - leucine rich repeats and calponin homology domain containing 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 84859 | Gene type: protein coding

About LRCH3

This gene has 19 transcripts (splice variants), 199 orthologues and 31 paralogues. Ubiquitous expression in ovary (RPKM 3.8), lymph node (RPKM 3.6) and 25 other tissues.

Summary

Involved in septin Cytoskeleton organization. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

LRCH3 Products(7)

mRNA Protein Name
NM_001363887.1 NP_001350816.1 DISP complex protein LRCH3 isoform 1
NM_001365715.1 NP_001352644.1 DISP complex protein LRCH3 isoform 3
NM_001365716.1 NP_001352645.1 DISP complex protein LRCH3 isoform 4
NM_001365717.1 NP_001352646.1 DISP complex protein LRCH3 isoform 5
NM_001365718.1 NP_001352647.1 DISP complex protein LRCH3 isoform 6
NM_001365719.2 NP_001352648.1 DISP complex protein LRCH3 isoform 7
NM_032773.4 NP_116162.1 DISP complex protein LRCH3 isoform 2

LRCH3 Protein Structure

LRR_1

LRR_1: Leucine Rich Repeat (130 - 150)

LRR_8

LRR_8: Leucine rich repeat (152 - 208)

CH

CH: Calponin homology (CH) domain (662 - 762)

  • 0
  • 200
  • 400
  • 600
  • 777 a.a.
Protein Preferred Names Protein Names

DISP complex protein LRCH3

leucine-rich repeat and calponin homology domain-containing protein 3

Related Diseases

Diseases Alias
Cardiomyopathy, Familial Hypertrophic, 2

Hypertrophic Cardiomyopathy 2

CMH2

Cardiomyopathy, Hypertrophic, 2

Cardiomyopathy Familial Hypertrophic 2

Cardiomyopathy, Familial Hypertrophic 2

Cardiomyopathy, Hypertrophic, Familial, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07779 LRCH3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LRCH3 RGD RGD:1306200
Mus musculus LRCH3 MGD MGI:1917394
Felis catus LRCH3 VGNC VGNC:63274
Bos taurus LRCH3 VGNC VGNC:30973
Macaca mulatta LRCH3 VGNC VGNC:74382
Canis familiaris LRCH3 VGNC VGNC:53078