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  2. BCAS1 - brain enriched myelin associated protein 1 Gene

BCAS1 - brain enriched myelin associated protein 1 Gene

Homo sapiens

Also known as AIBC1; NABC1; PMES-2

Gene ID: 8537 | Gene type: protein coding

About BCAS1

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:53,943,541-54,070,594 (from NCBI)

This gene has 11 transcripts (splice variants) and 125 orthologues. Biased expression in stomach (RPKM 58.5), colon (RPKM 41.1) and 7 other tissues.

Summary

This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast Cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast Cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]

BCAS1 Products(7)

mRNA Protein Name
NM_001316361.3 NP_001303290.1 breast carcinoma-amplified sequence 1 isoform 2
NM_001323347.2 NP_001310276.1 breast carcinoma-amplified sequence 1 isoform 2
NM_001366295.2 NP_001353224.1 breast carcinoma-amplified sequence 1 isoform 3
NM_001366296.2 NP_001353225.1 breast carcinoma-amplified sequence 1 isoform 4
NM_001366297.2 NP_001353226.1 breast carcinoma-amplified sequence 1 isoform 5
NM_001366298.2 NP_001353227.1 breast carcinoma-amplified sequence 1 isoform 6
NM_003657.4 NP_003648.2 breast carcinoma-amplified sequence 1 isoform 1
Protein Preferred Names Protein Names

breast carcinoma-amplified sequence 1

amplified and overexpressed in breast cancer

Related Diseases

Diseases Alias
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus BCAS1 MGD MGI:1924210
Macaca mulatta BCAS1 VGNC VGNC:98871
Rattus norvegicus BCAS1 RGD RGD:628644
Felis catus BCAS1 VGNC VGNC:98869
Canis familiaris BCAS1 VGNC VGNC:98867
Bos taurus BCAS1 VGNC VGNC:98868