BARX2 - BARX homeobox 2 Gene

Homo sapiens

Gene ID: 8538 | Gene type: protein coding

About BARX2

Cytogenetic location: 11q24.3 Genomic coordinates (GRCh38): 11:129,375,233-129,452,279 (from NCBI)

This gene has 2 transcripts (splice variants), 210 orthologues and 3 paralogues. Biased expression in esophagus (RPKM 46.6), salivary gland (RPKM 29.6) and 9 other tissues.

Summary

This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin Cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in Cancer progression. [provided by RefSeq, Jul 2008]

BARX2 Products(1)

mRNA	Protein	Name
NM_003658.5	NP_003649.2	homeobox protein BarH-like 2

BARX2 Protein Structure

Homeobox

0
100
200
279 a.a.

Protein Preferred Names

Protein Names

homeobox protein BarH-like 2

BarH-like homeobox 2

Related Diseases

Diseases

Alias

Jacobsen Syndrome

Chromosome 11q Deletion Syndrome	Partial 11q Monosomy Syndrome
Jacobsen Distal 11q Deletion Syndrome	JBS
11q Partial Monosomy Syndrome	Chromosome 11q Deletion
11q Deletion	11q Monosomy
Deletion 11q	Monosomy 11q
Partial Monosomy 11q	11q Deletion Disorder
11q Deletion Syndrome	11q Terminal Deletion Disorder
11q- Deletion Syndrome	11q23 Deletion Disorder
Jacobsen Thrombocytopenia	11q Terminal Deletion Syndrome
Del(11)(Q23.3)	Del(11)(Qter)
Distal Deletion 11q	Distal Monosomy 11q
Monosomy 11qter	Telomeric Deletion 11q
Paris-Trousseau Thrombocytopenia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01369	BARX2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	BARX2	RGD	RGD:1584840
Bos taurus	BARX2	VGNC	VGNC:26424
Felis catus	BARX2	VGNC	VGNC:69123
Canis familiaris	BARX2	VGNC	VGNC:38383
Mus musculus	BARX2	MGD	MGI:109617
Macaca mulatta	BARX2	VGNC	VGNC:107424

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