2. Gene
  3. TNKS1BP1 - tankyrase 1 binding protein 1 Gene

TNKS1BP1 - tankyrase 1 binding protein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TAB182

Gene ID: 85456 | Gene type: protein coding

About TNKS1BP1

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,299,642-57,324,952 (from NCBI)

This gene has 7 transcripts (splice variants), 112 orthologues and 1 paralogue. Ubiquitous expression in skin (RPKM 32.4), fat (RPKM 31.8) and 24 other tissues.

Summary

Enables ankyrin repeat binding activity and Enzyme binding activity. Involved in cellular response to ionizing radiation; double-strand break repair; and positive regulation of protein phosphorylation. Located in several cellular components, including actin cytoskeleton; adherens junction; and heterochromatin. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022]

TNKS1BP1 Products(1)

mRNA Protein Name
NM_033396.3 NP_203754.2 182 kDa tankyrase-1-binding protein

TNKS1BP1 Protein Structure

Tankyrase_bdg_C

Tankyrase_bdg_C: Tankyrase binding protein C terminal domain (1554 - 1726)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1729 a.a.
Protein Preferred Names Protein Names

182 kDa tankyrase-1-binding protein

tankyrase 1 binding protein 1, 182kDa

Related Diseases

Diseases Alias
Cherubism

CRBM

Familial Benign Giant-Cell Tumor Of The Jaw

Familial Fibrous Dysplasia Of Jaw

Familial Multilocular Cystic Disease Of The Jaws
Alcohol-Induced Mental Disorder

Psychoses, Alcoholic
Substance-Induced Psychosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14842 TNKS1BP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TNKS1BP1 MGD MGI:2446193
Rattus norvegicus TNKS1BP1 RGD RGD:1312021
Canis familiaris TNKS1BP1 VGNC VGNC:47682
Macaca mulatta TNKS1BP1 VGNC VGNC:79181
Felis catus TNKS1BP1 VGNC VGNC:66422
Bos taurus TNKS1BP1 VGNC VGNC:36185