2. Gene
  3. DIXDC1 - DIX domain containing 1 Gene

DIXDC1 - DIX domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CCD1

Gene ID: 85458 | Gene type: protein coding

About DIXDC1

Cytogenetic location: 11q23.1 Genomic coordinates (GRCh38): 11:111,927,315-112,022,653 (from NCBI)

This gene has 9 transcripts (splice variants), 273 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 11.3), endometrium (RPKM 10.0) and 23 other tissues.

Summary

The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

DIXDC1 Products(3)

mRNA Protein Name
NM_001037954.4 NP_001033043.1 dixin isoform a
NM_001278542.2 NP_001265471.1 dixin isoform c
NM_033425.5 NP_219493.1 dixin isoform b

DIXDC1 Protein Structure

CH

CH: Calponin homology (CH) domain (24 - 126)

DIX

DIX: DIX domain (598 - 678)

  • 0
  • 200
  • 400
  • 600
  • 682 a.a.
Protein Preferred Names Protein Names

dixin

coiled-coil protein DIX1

Related Diseases

Diseases Alias
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03785 DIXDC1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DIXDC1 VGNC VGNC:39969
Macaca mulatta DIXDC1 VGNC VGNC:71694
Bos taurus DIXDC1 VGNC VGNC:28077
Rattus norvegicus DIXDC1 RGD RGD:1309902
Mus musculus DIXDC1 MGD MGI:2679721
Felis catus DIXDC1 VGNC VGNC:102875