NOP14 - NOP14 nucleolar protein Gene

Homo sapiens

Also known as UTP2; NOL14; C4orf9; RES425; RES4-25

Gene ID: 8602 | Gene type: protein coding

About NOP14

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:2,937,936-2,963,406 (from NCBI)

This gene has 5 transcripts (splice variants) and 199 orthologues. Ubiquitous expression in lymph node (RPKM 10.9), appendix (RPKM 9.8) and 25 other tissues.

Summary

This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic Cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

NOP14 Products(3)

mRNA	Protein	Name
NM_001291978.2	NP_001278907.1	nucleolar protein 14 isoform 1
NM_001291979.2	NP_001278908.1	nucleolar protein 14 isoform 2
NM_003703.3	NP_003694.1	nucleolar protein 14 isoform 1

NOP14 Protein Structure

Nop14

0
200
400
600
800
857 a.a.

Protein Preferred Names

Protein Names

nucleolar protein 14

NOP14 nucleolar protein homolog

Related Diseases

Diseases

Alias

Bowen-Conradi Syndrome

BWCNS	Bowen Hutterite Syndrome
Bowen-Conradi Hutterite Syndrome	Bowen Syndrome, Hutterite Type
Bowen Hutterite Syndrome, Formerly	Hutterite Syndrome
Bowen Syndrome Hutterite Type	Fetal Growth Retardation

Pancreatic Cancer

Pancreatic Carcinoma	Carcinoma Of Pancreas
Familial Pancreatic Carcinoma	Pancreatic Neoplasm
Pancreatic Carcinoma, Familial	Malignant Neoplasm Of Pancreas
Pancreatic Acinar Carcinoma	Pancreatic Tumor
Familial Pancreatic Cancer	Neoplasm Of The Pancreas
Cancer Of The Pancreas	Pancreatic Carcinoma, Somatic
Pancreatic Cancer, Somatic	Ca Body Of Pancreas
Ca Head Of Pancreas	Ca Tail Of Pancreas
Malignant Neoplasm Of Body Of Pancreas	Malignant Neoplasm Of Head Of Pancreas
Malignant Neoplasm Of Tail Of Pancreas	Pancreas Neoplasm
Exocrine Cancer	Exocrine Pancreas Carcinoma
Hereditary Pancreatic Cancer	Hereditary Pancreatic Carcinoma
PNCA	Pancreatic Cancer, Susceptibility To
Carcinoma Of Head Of Pancreas	Pancreatic Neoplasms
Pancreatic Tumors	Cancer, Pancreatic
Cancer Of Pancreas	Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09427	NOP14 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	NOP14	VGNC	VGNC:75194
Bos taurus	NOP14	VGNC	VGNC:32165
Rattus norvegicus	NOP14	RGD	RGD:1305605
Canis familiaris	NOP14	VGNC	VGNC:43887
Mus musculus	NOP14	MGD	MGI:1922666
Felis catus	NOP14	VGNC	VGNC:63856

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