2. Gene
  3. PRPF4B - pre-mRNA processing factor 4B Gene

PRPF4B - pre-mRNA processing factor 4B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PR4H; PRP4; PRP4H; PRP4K; dJ1013A10.1

Gene ID: 8899 | Gene type: protein coding

About PRPF4B

Cytogenetic location: 6p25.2 Genomic coordinates (GRCh38): 6:4,021,300-4,064,983 (from NCBI)

This gene has 9 transcripts (splice variants), 240 orthologues and 26 paralogues. Ubiquitous expression in bone marrow (RPKM 15.0), lymph node (RPKM 13.5) and 25 other tissues.

Summary

Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (CLK) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]

PRPF4B Products(1)

mRNA Protein Name
NM_003913.5 NP_003904.3 serine/threonine-protein kinase PRP4 homolog

PRPF4B Protein Structure

Pkinase

Pkinase: Protein kinase domain (691 - 1003)

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  • 1007 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PRP4 homolog

PRP4 kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11214 PRPF4B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PRPF4B VGNC VGNC:64377
Canis familiaris PRPF4B VGNC VGNC:45028
Rattus norvegicus PRPF4B RGD RGD:1307784
Bos taurus PRPF4B VGNC VGNC:33381
Macaca mulatta PRPF4B VGNC VGNC:76276
Mus musculus PRPF4B MGD MGI:109584