2. Gene
  3. FUBP3 - far upstream element binding protein 3 Gene

FUBP3 - far upstream element binding protein 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FBP3

Gene ID: 8939 | Gene type: protein coding

About FUBP3

Cytogenetic location: 9q34.11-q34.12 Genomic coordinates (GRCh38): 9:130,579,577-130,638,352 (from NCBI)

This gene has 8 transcripts (splice variants), 276 orthologues and 12 paralogues. Ubiquitous expression in thyroid (RPKM 15.5), brain (RPKM 11.3) and 25 other tissues.

Summary

Enables single-stranded DNA binding activity. Involved in positive regulation of gene expression; positive regulation of transcription, DNA-templated; and transcription, DNA-templated. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FUBP3 Products(1)

mRNA Protein Name
NM_003934.2 NP_003925.1 far upstream element-binding protein 3

FUBP3 Protein Structure

KH_1

KH_1: KH domain (79 - 141)

KH_1

KH_1: KH domain (165 - 228)

KH_1

KH_1: KH domain (256 - 315)

KH_1

KH_1: KH domain (357 - 421)

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  • 572 a.a.
Protein Preferred Names Protein Names

far upstream element-binding protein 3

FUSE-binding protein 3

Related Diseases

Diseases Alias
Calvarial Doughnut Lesions With Bone Fragility

Calvarial Doughnut Lesions With Bone Fragility With Or Without Spondylometaphyseal Dysplasia

Calvarial Doughnut Lesions-Bone Fragility Syndrome

CDL

Doughnut Lesions Of Skull, Familial

Calvarial Doughnut Lesions With Bone Fragility And Spondylometaphyseal Dysplasia

Familial Doughnut Lesions Of Skull

CDLSMD
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05142 FUBP3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FUBP3 RGD RGD:1307004
Felis catus FUBP3 VGNC VGNC:102930
Bos taurus FUBP3 VGNC VGNC:59216
Mus musculus FUBP3 MGD MGI:2443699
Canis familiaris FUBP3 VGNC VGNC:55565
Macaca mulatta FUBP3 VGNC VGNC:103266