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  2. H2BC11 - H2B clustered histone 11 Gene

H2BC11 - H2B clustered histone 11 Gene

Homo sapiens

Also known as H2BJ; H2B/r; H2BFR; HIST1H2BJ

Gene ID: 8970 | Gene type: protein coding

About H2BC11

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:27,132,316-27,132,795 (from NCBI)

This gene has 3 transcripts (splice variants), 126 orthologues and 21 paralogues.

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]

H2BC11 Products(1)

mRNA Protein Name
NM_021058.4 NP_066402.2 histone H2B type 1-J

H2BC11 Protein Structure

Histone

Histone: Core histone H2A/H2B/H3/H4 (32 - 101)

  • 0
  • 100
  • 126 a.a.
Protein Preferred Names Protein Names

histone H2B type 1-J

H2B histone family, member R

Recombinant H2BC11 Proteins

Cat. No. Product Name Accession Purity
HY-P72329 H2BC11 Protein, Human P06899 (P2-K126) ≥95%

Related Diseases

Diseases Alias
Arteriovenous Malformations Of The Brain

Cerebral Arteriovenous Malformation

Intracranial Arteriovenous Malformation

Intracranial Hemorrhage In Brain Cerebrovascular Malformations, Susceptibility To

Intracranial Arteriovenous Malformations

Bavm

Cerebral Arteriovenous Malformations

Intracranial Hemorrhage In Brain Cerebrovascular Malformations

Arteriovenous Malformation Of The Brain, Somatic

Intracranial Avm

Arteriovenous Malformations Cerebral

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus H2BC11 RGD RGD:1562346
Mus musculus H2BC11 MGD MGI:2448415