CLIC3 - chloride intracellular channel 3 Gene

Homo sapiens

Gene ID: 9022 | Gene type: protein coding

About CLIC3

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,994,608-136,996,568 (from NCBI)

This gene has 3 transcripts (splice variants), 225 orthologues and 14 paralogues. Biased expression in esophagus (RPKM 23.8), thyroid (RPKM 21.4) and 5 other tissues.

Summary

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008]

CLIC3 Products(1)

mRNA	Protein	Name
NM_004669.3	NP_004660.2	chloride intracellular channel protein 3

CLIC3 Protein Structure

GST_N_3

GST_C_2

0
100
200
236 a.a.

Protein Preferred Names

Protein Names

chloride intracellular channel protein 3

Recombinant CLIC3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7857	CLIC3 Protein, Human (His)	O95833 (M1-R236)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02805	CLIC3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CLIC3	RGD	RGD:1307249
Macaca mulatta	CLIC3	VGNC	VGNC:71255
Canis familiaris	CLIC3	VGNC	VGNC:39339
Bos taurus	CLIC3	VGNC	VGNC:27441
Mus musculus	CLIC3	MGD	MGI:1916704
Felis catus	CLIC3	VGNC	VGNC:60960
Others	CLIC3	NCBI

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