1. Gene
  2. CTU1 - cytosolic thiouridylase subunit 1 Gene

CTU1 - cytosolic thiouridylase subunit 1 Gene

Homo sapiens

Also known as NCS6; ATPBD3

Gene ID: 90353 | Gene type: protein coding

About CTU1

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,097,606-51,108,409 (from NCBI)

This gene has 1 transcript (splice variant) and 179 orthologues. Ubiquitous expression in kidney (RPKM 1.5), spleen (RPKM 1.3) and 25 other tissues.

Summary

Predicted to enable tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Predicted to be part of cytosolic tRNA wobble base thiouridylase complex. [provided by Alliance of Genome Resources, Apr 2022]

CTU1 Products(1)

mRNA Protein Name
NM_145232.4 NP_660275.2 cytoplasmic tRNA 2-thiolation protein 1

CTU1 Protein Structure

ATP_bind_3

ATP_bind_3: PP-loop family (54 - 240)

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  • 348 a.a.
Protein Preferred Names Protein Names

cytoplasmic tRNA 2-thiolation protein 1

ATP binding domain 3

Related Diseases

Diseases Alias
Neuropathy, Hereditary Sensory And Autonomic, Type Iii

Familial Dysautonomia

Riley-Day Syndrome

Dysautonomia, Familial

HSAN3

Hsan Iii

Fd

Hereditary Sensory And Autonomic Neuropathy Type Iii

Dys

Hereditary Sensory And Autonomic Neuropathy 3

Riley Day Syndrome

Familial Autonomic Nervous Dysfunction

Hereditary Sensory Autonomic Neuropathy Type Iii

Hsan 3

Hsn 3

Hereditary Sensory Neuropathy Type 3

Hsan Type Iii

Hsn-Iii

Hereditary Sensory And Autonomic Neuropathy Type 3

Neuropathy, Hereditary Sensory And Autonomic, 3

Hsn Iii

Dysautonomia Familial

Neuropathy, Sensory And Autonomic, Hereditary, Type Iii

Hsan3 - [Hereditary Sensory And Autonomic Neuropathy Type 3]

Spinal Cord Ependymoma

Ependymal Neoplasm Of The Spinal Cord

Spinal Ependymoma

Ependymoma Of Spinal Cord

Dubowitz Syndrome

Dubowitz'S Syndrome

Dwarfism-Eczema-Peculiar Facies Syndrome

Intrauterine Growth Restriction, Short Stature, Microcephaly, Mild Intellectual Disability With Behavior Problems, Eczema, And Unusual And Distinctive Faci

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus CTU1 MGD MGI:2385277
Macaca mulatta CTU1 VGNC VGNC:109612
Rattus norvegicus CTU1 RGD RGD:1308740