2. Gene
  3. IGFN1 - immunoglobulin like and fibronectin type III domain containing 1 Gene

IGFN1 - immunoglobulin like and fibronectin type III domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EEF1A2BP1

Gene ID: 91156 | Gene type: protein coding

About IGFN1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,190,824-201,228,952 (from NCBI)

This gene has 5 transcripts (splice variants), 141 orthologues and 9 paralogues. Biased expression in endometrium (RPKM 9.4), testis (RPKM 3.4) and 5 other tissues.

Summary

Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules; retina layer formation; and synapse assembly. Predicted to be located in Z disc and nucleus. Predicted to be active in synapse. [provided by Alliance of Genome Resources, Apr 2022]

IGFN1 Products(2)

mRNA Protein Name
NM_001164586.2 NP_001158058.1 immunoglobulin-like and fibronectin type III domain-containing protein 1 isoform 1
NM_001367841.1 NP_001354770.1 immunoglobulin-like and fibronectin type III domain-containing protein 1 isoform 2

IGFN1 Protein Structure

I-set

I-set: Immunoglobulin I-set domain (74 - 156)

I-set

I-set: Immunoglobulin I-set domain (166 - 257)

fn3

fn3: Fibronectin type III domain (268 - 346)

fn3

fn3: Fibronectin type III domain (363 - 445)

fn3

fn3: Fibronectin type III domain (465 - 548)

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  • 608 a.a.
Protein Preferred Names Protein Names

immunoglobulin-like and fibronectin type III domain-containing protein 1

EEF1A2-binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06636 IGFN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IGFN1 RGD RGD:1565384
Felis catus IGFN1 VGNC VGNC:62891
Bos taurus IGFN1 VGNC VGNC:59401
Macaca mulatta IGFN1 VGNC VGNC:99976
Mus musculus IGFN1 MGD MGI:3045352