SCAF11 - SR-related CTD associated factor 11 Gene

Homo sapiens

Also known as SIP1; CASP11; SFRS2IP; SRRP129; SRSF2IP

Gene ID: 9169 | Gene type: protein coding

About SCAF11

Cytogenetic location: 12q12 Genomic coordinates (GRCh38): 12:45,919,131-45,992,059 (from NCBI)

This gene has 15 transcripts (splice variants), 203 orthologues and 2 paralogues. Ubiquitous expression in lymph node (RPKM 15.2), appendix (RPKM 14.4) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in spliceosomal complex assembly. Located in nuclear body and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

SCAF11 Products(1)

mRNA	Protein	Name
NM_004719.3	NP_004710.2	protein SCAF11

SCAF11 Protein Structure

zf-RING_2

0
300
600
900
1200
1463 a.a.

Protein Preferred Names

Protein Names

protein SCAF11

CTD-associated SR protein 11

Related Diseases

Diseases

Alias

Corneal Endothelial Dystrophy

Congenital Hereditary Endothelial Dystrophy Of Cornea	Chandler Syndrome
CHED	Chandler'S Syndrome
Endothelial Corneal Dystrophy	Ched2
Maumenee Corneal Dystrophy	Corneal Dystrophy, Congenital Hereditary Endothelial
Dystrophy Of Corneal Endothelium	Corneal Endothelial Dystrophy 2
Corneal Endothelial Dystrophy 2, Autosomal Recessive, Formerly	Ched2, Formerly
Corneal Endothelial Dystrophy, Autosomal Recessive	Endothelial Dystrophy
Posterior Membrane Corneal Dystrophy	Corneal Endothelial Dystrophy Type 2
Congenital Hereditary Endothelial Dystrophy Of The Cornea	Congenital Hereditary Endothelial Dystrophy Type Ii
Autosomal Recessive Ched	Autosomal Recessive Congenital Hereditary Endothelial Dystrophy
Chedii	Congenital Hereditary Endothelial Dystrophy Type 2
Infantile Hereditary Endothelial Dystrophy	Congenital Hereditary Endothelial Corneal Dystrophy
Corneal Endothelial Dystrophy 2, Autosomal Recessive	Iridocorneal Endothelial Syndrome
Dystrophy, Corneal, Endothelial	Corneal Endothelial Dystrophy 1, Autosomal Dominant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12475	SCAF11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SCAF11	MGD	MGI:1919443
Felis catus	SCAF11	VGNC	VGNC:64892
Bos taurus	SCAF11	VGNC	VGNC:34314
Rattus norvegicus	SCAF11	RGD	RGD:1598325
Macaca mulatta	SCAF11	VGNC	VGNC:77002
Canis familiaris	SCAF11	VGNC	VGNC:45889

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