GCNT3 - glucosaminyl (N-acetyl) transferase 3, mucin type Gene

Homo sapiens

Also known as GNTM; C24GNT; C2GNT2; C2GNTM; C2/4GnT

Gene ID: 9245 | Gene type: protein coding

About GCNT3

Cytogenetic location: 15q22.2 Genomic coordinates (GRCh38): 15:59,549,039-59,622,723 (from NCBI)

This gene has 10 transcripts (splice variants), 274 orthologues and 8 paralogues. Biased expression in colon (RPKM 74.9), small intestine (RPKM 64.2) and 7 other tissues.

Summary

This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009]

GCNT3 Products(1)

mRNA	Protein	Name
NM_004751.3	NP_004742.1	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

GCNT3 Protein Structure

Branch

0
100
200
300
400
438 a.a.

Protein Preferred Names

Protein Names

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

C2GnT-mucin type

Related Diseases

Diseases

Alias

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05341	GCNT3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GCNT3	RGD	RGD:631333
Macaca mulatta	GCNT3	VGNC	VGNC:84342
Felis catus	GCNT3	VGNC	VGNC:104351
Mus musculus	GCNT3	MGD	MGI:1919327
Canis familiaris	GCNT3	VGNC	VGNC:59113

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