2. Gene
  3. SP140L - SP140 nuclear body protein like Gene

SP140L - SP140 nuclear body protein like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 93349 | Gene type: protein coding

About SP140L

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:230,327,193-230,403,732 (from NCBI)

This gene has 10 transcripts (splice variants), 220 orthologues and 20 paralogues. Broad expression in lymph node (RPKM 8.7), spleen (RPKM 8.3) and 24 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SP140L Products(6)

mRNA Protein Name
NM_001308162.3 NP_001295091.1 nuclear body protein SP140-like protein isoform 2
NM_001308163.3 NP_001295092.1 nuclear body protein SP140-like protein isoform 3
NM_001352892.2 NP_001339821.1 nuclear body protein SP140-like protein isoform 4
NM_001352893.2 NP_001339822.1 nuclear body protein SP140-like protein isoform 5
NM_001352894.2 NP_001339823.1 nuclear body protein SP140-like protein isoform 6
NM_138402.6 NP_612411.4 nuclear body protein SP140-like protein isoform 1

SP140L Protein Structure

HSR

HSR: HSR domain (49 - 150)

SAND

SAND: SAND domain (293 - 373)

PHD

PHD: PHD-finger (406 - 448)

Bromodomain

Bromodomain: Bromodomain (507 - 549)

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  • 580 a.a.
Protein Preferred Names Protein Names

nuclear body protein SP140-like protein

SP140L-1 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13604 SP140L Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SP140L MGD MGI:3702467