2. Gene
  3. PGS1 - phosphatidylglycerophosphate synthase 1 Gene

PGS1 - phosphatidylglycerophosphate synthase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 9489 | Gene type: protein coding

About PGS1

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:78,378,649-78,424,659 (from NCBI)

This gene has 15 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in bone marrow (RPKM 9.6), appendix (RPKM 8.4) and 25 other tissues.

Summary

Predicted to enable CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity and calcium ion binding activity. Predicted to be involved in cardiolipin biosynthetic process and diacylglycerol metabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

PGS1 Products(1)

mRNA Protein Name
NM_024419.5 NP_077733.3 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial precursor

PGS1 Protein Structure

PLDc_2

PLDc_2: PLD-like domain (111 - 259)

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  • 556 a.a.
Protein Preferred Names Protein Names

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

PGP synthase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10401 PGS1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PGS1 VGNC VGNC:64127
Rattus norvegicus PGS1 RGD RGD:1305052
Bos taurus PGS1 VGNC VGNC:32803
Macaca mulatta PGS1 VGNC VGNC:75890
Canis familiaris PGS1 VGNC VGNC:44472
Mus musculus PGS1 MGD MGI:1921701