1. Gene
  2. MTSS1 - MTSS I-BAR domain containing 1 Gene

MTSS1 - MTSS I-BAR domain containing 1 Gene

Homo sapiens

Also known as MIM; MIMA; MIMB

Gene ID: 9788 | Gene type: protein coding

About MTSS1

Cytogenetic location: 8q24.13 Genomic coordinates (GRCh38): 8:124,550,784-124,728,473 (from NCBI)

This gene has 18 transcripts (splice variants), 275 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 5.7), adrenal (RPKM 5.6) and 25 other tissues.

Summary

Enables actin monomer binding activity; identical protein binding activity; and signaling receptor binding activity. Predicted to be involved in cellular response to fluid shear stress; negative regulation of epithelial cell proliferation; and urogenital system development. Predicted to act upstream of or within several processes, including actin filament polymerization; adherens junction maintenance; and magnesium ion homeostasis. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

MTSS1 Products(12)

mRNA Protein Name
NM_001282971.2 NP_001269900.1 protein MTSS 1 isoform 1
NM_001282974.2 NP_001269903.1 protein MTSS 1 isoform 3
NM_001363294.2 NP_001350223.1 protein MTSS 1 isoform 4
NM_001363295.2 NP_001350224.1 protein MTSS 1 isoform 5
NM_001363296.2 NP_001350225.1 protein MTSS 1 isoform 6
NM_001363297.2 NP_001350226.1 protein MTSS 1 isoform 7
NM_001363298.2 NP_001350227.1 protein MTSS 1 isoform 8
NM_001363299.2 NP_001350228.1 protein MTSS 1 isoform 9
NM_001363300.2 NP_001350229.1 protein MTSS 1 isoform 10
NM_001363301.2 NP_001350230.1 protein MTSS 1 isoform 11
NM_001363302.2 NP_001350231.1 protein MTSS 1 isoform 12
NM_014751.6 NP_055566.3 protein MTSS 1 isoform 2

MTSS1 Protein Structure

IMD

IMD: IRSp53/MIM homology domain (16 - 237)

WH2

WH2: WH2 motif (725 - 750)

  • 0
  • 200
  • 400
  • 600
  • 755 a.a.
Protein Preferred Names Protein Names

protein MTSS 1

MTSS1, I-BAR domain containing

Recombinant MTSS1 Proteins

Cat. No. Product Name Accession Purity
HY-P75930 MTSS1 Protein, Human (His) EAW92073 (M1-S250) ≥95%

Related Diseases

Diseases Alias
Oropharyngeal Anthrax
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus MTSS1 MGD MGI:2384818
Canis familiaris MTSS1 VGNC VGNC:43493
Bos taurus MTSS1 VGNC VGNC:31752
Macaca mulatta MTSS1 VGNC VGNC:74995
Felis catus MTSS1 VGNC VGNC:63660
Rattus norvegicus MTSS1 RGD RGD:1309883
Others MTSS1 NCBI