SPOCK2 - SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 Gene

Homo sapiens

Also known as testican-2

Gene ID: 9806 | Gene type: protein coding

About SPOCK2

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:72,059,034-72,089,032 (from NCBI)

This gene has 8 transcripts (splice variants), 210 orthologues and 3 paralogues. Biased expression in lung (RPKM 58.9), brain (RPKM 55.4) and 13 other tissues.

Summary

This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

SPOCK2 Products(3)

mRNA	Protein	Name
NM_001134434.1	NP_001127906.1	testican-2 isoform 1 precursor
NM_001244950.2	NP_001231879.1	testican-2 isoform 2 precursor
NM_014767.2	NP_055582.1	testican-2 isoform 2 precursor

SPOCK2 Protein Structure

Kazal_2

SPARC_Ca_bdg

Thyroglobulin_1

0
100
200
300
400
424 a.a.

Protein Preferred Names

Protein Names

testican-2

SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13696	SPOCK2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SPOCK2	VGNC	VGNC:46751
Macaca mulatta	SPOCK2	VGNC	VGNC:106105
Rattus norvegicus	SPOCK2	RGD	RGD:1308568
Mus musculus	SPOCK2	MGD	MGI:1891351
Bos taurus	SPOCK2	VGNC	VGNC:35226

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