2. Gene
  3. MED24 - mediator complex subunit 24 Gene

MED24 - mediator complex subunit 24 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MED5; CRSP4; ARC100; THRAP4; CRSP100; DRIP100; TRAP100

Gene ID: 9862 | Gene type: protein coding

About MED24

Cytogenetic location: 17q21.1 Genomic coordinates (GRCh38): 17:40,019,104-40,054,408 (from NCBI)

This gene has 33 transcripts (splice variants) and 220 orthologues. Ubiquitous expression in testis (RPKM 18.9), brain (RPKM 13.4) and 25 other tissues.

Summary

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

MED24 Products(4)

mRNA Protein Name
NM_001079518.2 NP_001072986.1 mediator of RNA polymerase II transcription subunit 24 isoform 2
NM_001267797.2 NP_001254726.1 mediator of RNA polymerase II transcription subunit 24 isoform 2
NM_001330211.2 NP_001317140.1 mediator of RNA polymerase II transcription subunit 24 isoform 3
NM_014815.4 NP_055630.2 mediator of RNA polymerase II transcription subunit 24 isoform 1

MED24 Protein Structure

Med24_N

Med24_N: Mediator complex subunit 24 N-terminal (1 - 987)

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  • 989 a.a.
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 24

CRSP complex subunit 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08295 MED24 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MED24 RGD RGD:1564565
Bos taurus MED24 VGNC VGNC:31361
Felis catus MED24 VGNC VGNC:63438
Mus musculus MED24 MGD MGI:1344385
Canis familiaris MED24 VGNC VGNC:43132