2. Gene
  3. RABGAP1L - RAB GTPase activating protein 1 like Gene

RABGAP1L - RAB GTPase activating protein 1 like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HHL; TBC1D18

Gene ID: 9910 | Gene type: protein coding

About RABGAP1L

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:174,159,520-174,995,308 (from NCBI)

This gene has 23 transcripts (splice variants), 277 orthologues and 45 paralogues. Ubiquitous expression in heart (RPKM 7.5), brain (RPKM 5.9) and 25 other tissues.

Summary

Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within regulation of protein localization. Located in Golgi apparatus; early endosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RABGAP1L Products(19)

mRNA Protein Name
NM_001035230.3 NP_001030307.1 rab GTPase-activating protein 1-like isoform B
NM_001243763.2 NP_001230692.1 rab GTPase-activating protein 1-like isoform B
NM_001243764.2 NP_001230693.1 rab GTPase-activating protein 1-like isoform D
NM_001243765.2 NP_001230694.1 rab GTPase-activating protein 1-like isoform C
NM_001330989.2 NP_001317918.1 rab GTPase-activating protein 1-like isoform E
NM_001366445.1 NP_001353374.1 rab GTPase-activating protein 1-like isoform F
NM_001366446.1 NP_001353375.1 rab GTPase-activating protein 1-like isoform G
NM_001366447.1 NP_001353376.1 rab GTPase-activating protein 1-like isoform H
NM_001366448.1 NP_001353377.1 rab GTPase-activating protein 1-like isoform I
NM_001366449.1 NP_001353378.1 rab GTPase-activating protein 1-like isoform J
NM_001366450.1 NP_001353379.1 rab GTPase-activating protein 1-like isoform K
NM_001366451.1 NP_001353380.1 rab GTPase-activating protein 1-like isoform L
NM_001366452.1 NP_001353381.1 rab GTPase-activating protein 1-like isoform M
NM_001366453.1 NP_001353382.1 rab GTPase-activating protein 1-like isoform N
NM_001366454.1 NP_001353383.1 rab GTPase-activating protein 1-like isoform O
NM_001366455.1 NP_001353384.1 rab GTPase-activating protein 1-like isoform P
NM_001366456.1 NP_001353385.1 rab GTPase-activating protein 1-like isoform Q
NM_001366457.1 NP_001353386.1 rab GTPase-activating protein 1-like isoform R
NM_014857.5 NP_055672.3 rab GTPase-activating protein 1-like isoform A

RABGAP1L Protein Structure

PID

PID: Phosphotyrosine interaction domain (PTB/PID) (135 - 245)

DUF3694

DUF3694: Kinesin protein (290 - 421)

RabGAP-TBC

RabGAP-TBC: Rab-GTPase-TBC domain (542 - 744)

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  • 815 a.a.
Protein Preferred Names Protein Names

rab GTPase-activating protein 1-like

TBC1 domain family, member 18

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11585 RABGAP1L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RABGAP1L RGD RGD:1304620
Mus musculus RABGAP1L MGD MGI:1352507
Macaca mulatta RABGAP1L VGNC VGNC:76528