1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. KLTWQELYQLKYKGI

KLTWQELYQLKYKGI (QK) is a VEGF mimicking peptide, binds to the VEGF receptors and competes with VEGF. KLTWQELYQLKYKGI is active in gastric ulcer healing in rodents when administered either orally or systemically. KLTWQELYQLKYKGI shows the ability to induce capillary formation and organization in vitro.

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Custom Peptide Synthesis

KLTWQELYQLKYKGI Chemical Structure

KLTWQELYQLKYKGI Chemical Structure

CAS No. : 917760-16-8

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10 mg USD 140 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

KLTWQELYQLKYKGI (QK) is a VEGF mimicking peptide, binds to the VEGF receptors and competes with VEGF. KLTWQELYQLKYKGI is active in gastric ulcer healing in rodents when administered either orally or systemically. KLTWQELYQLKYKGI shows the ability to induce capillary formation and organization in vitro[1].

Molecular Weight

1911.25

Formula

C92H143N21O23

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Leu-Thr-Trp-Gln-Glu-Leu-Tyr-Gln-Leu-Lys-Tyr-Lys-Gly-Ile

Sequence Shortening

KLTWQELYQLKYKGI

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (52.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5232 mL 2.6161 mL 5.2322 mL
5 mM 0.1046 mL 0.5232 mL 1.0464 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.5232 mL 2.6161 mL 5.2322 mL 13.0804 mL
5 mM 0.1046 mL 0.5232 mL 1.0464 mL 2.6161 mL
10 mM 0.0523 mL 0.2616 mL 0.5232 mL 1.3080 mL
15 mM 0.0349 mL 0.1744 mL 0.3488 mL 0.8720 mL
20 mM 0.0262 mL 0.1308 mL 0.2616 mL 0.6540 mL
25 mM 0.0209 mL 0.1046 mL 0.2093 mL 0.5232 mL
30 mM 0.0174 mL 0.0872 mL 0.1744 mL 0.4360 mL
40 mM 0.0131 mL 0.0654 mL 0.1308 mL 0.3270 mL
50 mM 0.0105 mL 0.0523 mL 0.1046 mL 0.2616 mL
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KLTWQELYQLKYKGI Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KLTWQELYQLKYKGI
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