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  2. Antibody-Drug Conjugates (ADCs)
  3. MC-VC-PABC-amide-PEG1-CH2-CC-885

MC-VC-PABC-amide-PEG1-CH2-CC-885 

Cat. No.: HY-145448 Purity: 99.57%
COA Handling Instructions

MC-VC-PABC-amide-PEG1-CH2-CC-885 is a neodegrader.

For research use only. We do not sell to patients.

MC-VC-PABC-amide-PEG1-CH2-CC-885 Chemical Structure

MC-VC-PABC-amide-PEG1-CH2-CC-885 Chemical Structure

CAS No. : 2722697-82-5

Size Price Stock Quantity
5 mg USD 956 In-stock
10 mg USD 1625 In-stock
25 mg USD 3412 In-stock
50 mg USD 5800 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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  • Purity & Documentation

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Description

MC-VC-PABC-amide-PEG1-CH2-CC-885 is a neodegrader[1].

Molecular Weight

1126.65

Formula

C55H68ClN11O13

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=CC=C(CNC(NC3=CC(Cl)=C(C=C3)CCOCCN(C)C(OCC4=CC=C(C=C4)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)=O)=O)C=C2CN1C6C(NC(CC6)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (88.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8876 mL 4.4379 mL 8.8759 mL
5 mM 0.1775 mL 0.8876 mL 1.7752 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.8876 mL 4.4379 mL 8.8759 mL 22.1897 mL
5 mM 0.1775 mL 0.8876 mL 1.7752 mL 4.4379 mL
10 mM 0.0888 mL 0.4438 mL 0.8876 mL 2.2190 mL
15 mM 0.0592 mL 0.2959 mL 0.5917 mL 1.4793 mL
20 mM 0.0444 mL 0.2219 mL 0.4438 mL 1.1095 mL
25 mM 0.0355 mL 0.1775 mL 0.3550 mL 0.8876 mL
30 mM 0.0296 mL 0.1479 mL 0.2959 mL 0.7397 mL
40 mM 0.0222 mL 0.1109 mL 0.2219 mL 0.5547 mL
50 mM 0.0178 mL 0.0888 mL 0.1775 mL 0.4438 mL
60 mM 0.0148 mL 0.0740 mL 0.1479 mL 0.3698 mL
80 mM 0.0111 mL 0.0555 mL 0.1109 mL 0.2774 mL
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MC-VC-PABC-amide-PEG1-CH2-CC-885 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MC-VC-PABC-amide-PEG1-CH2-CC-885
Cat. No.:
HY-145448
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