MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885

Cat. No.: HY-160497 Purity: 99.63%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 (Comp Ie) is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC).

For research use only. We do not sell to patients.

MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 Chemical Structure

CAS No. : 2722697-86-9

Size	Price	Stock	Quantity
1 mg	USD 900	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 2470	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 (Comp Ie) is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC)^[1].

Molecular Weight

1133.55

Formula

C₅₃H₆₁ClN₈O₁₈

CAS No.

2722697-86-9

Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=CC=C(CNC(NC3=CC(Cl)=C(C=C3)CCOCCN(C)C(OCC4=CC(NC(CCNC(CCCCCN5C(C=CC5=O)=O)=O)=O)=C(C=C4)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=O)=O)C=C2CN1C7C(NC(CC7)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (88.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.8822 mL	4.4109 mL	8.8218 mL
5 mM	0.1764 mL	0.8822 mL	1.7644 mL
10 mM	0.0882 mL	0.4411 mL	0.8822 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.63%

Select Batch:

Data Sheet (266 KB) SDS (0 KB)

COA (246 KB) HNMR (446 KB) RP-HPLC (221 KB) LCMS (102 KB)

Handling Instructions (2659 KB)

References

[1]. Nathan FISHKIN, et al. Neodegrader conjugates. Patent WO2021198965.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.8822 mL	4.4109 mL	8.8218 mL	22.0546 mL
	5 mM	0.1764 mL	0.8822 mL	1.7644 mL	4.4109 mL
	10 mM	0.0882 mL	0.4411 mL	0.8822 mL	2.2055 mL
	15 mM	0.0588 mL	0.2941 mL	0.5881 mL	1.4703 mL
	20 mM	0.0441 mL	0.2205 mL	0.4411 mL	1.1027 mL
	25 mM	0.0353 mL	0.1764 mL	0.3529 mL	0.8822 mL
	30 mM	0.0294 mL	0.1470 mL	0.2941 mL	0.7352 mL
	40 mM	0.0221 mL	0.1103 mL	0.2205 mL	0.5514 mL
	50 mM	0.0176 mL	0.0882 mL	0.1764 mL	0.4411 mL
	60 mM	0.0147 mL	0.0735 mL	0.1470 mL	0.3676 mL
	80 mM	0.0110 mL	0.0551 mL	0.1103 mL	0.2757 mL