2. Academic Validation
  3. Identification of the cockroach neuropeptide Pea-CAH-II as a second adipokinetic hormone in the firebug Pyrrhocoris apterus

Identification of the cockroach neuropeptide Pea-CAH-II as a second adipokinetic hormone in the firebug Pyrrhocoris apterus

  • Peptides. 2002 Mar;23(3):585-7. doi: 10.1016/s0196-9781(01)00627-1.
Dalibor Kodrík 1,  Petr Simek,  Ludek Lepsa,  Radomír Socha
Affiliations

Affiliation

  • 1 Institute of Entomology, Academy of Sciences, Branisovská 31, CZ-370 05, Ceské Budejovice, Czech Republic. [email protected]
PMID: 11836011 DOI: 10.1016/s0196-9781(01)00627-1
Abstract

A new member of the AKH/RPCH family was isolated from the corpora cardiaca of the firebug Pyrrhocoris apterus. It is the second adipokinetic peptide identified in this species. The peptide was characterized and its structure was deduced from the multiple MS(N) electrospray mass spectra as that of an octapeptide with the sequence pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-NH(2.) The peptide differs from the original P. apterus AKH (Pya-AKH) by one amino acid in position 3. Topical application and/or injection of the peptide induced lipid mobilization, but was inactive in mobilization of carbohydrates.

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