2. Academic Validation
  3. Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys

Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys

  • J Nat Prod. 1992 Dec;55(12):1776-8. doi: 10.1021/np50090a011.
T Konoshima 1,  M Kokumai,  M Kozuka,  H Tokuda,  H Nishino,  A Iwashima
Affiliations

Affiliation

  • 1 Kyoto Pharmaceutical University, Japan.
PMID: 1294698 DOI: 10.1021/np50090a011
Abstract

Afromosin [1] and soyasaponin I [2] isolated from Wistaria brachybotrys exhibited remarkable inhibitory effects on mouse skin tumor promotion, and afromosin also exhibited a significant inhibitory effect on pulmonary tumor promotion. The combined effects of these compounds on the two-stage skin carcinogenesis were also examined, and it was concluded that the combination of 1 with 2 enhanced the inhibitory effect.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-119846
    Anticancer Agent